Literature DB >> 8594689

Japanese poor metabolizers of proguanil do not have an increased risk of malaria chemoprophylaxis breakthrough.

E K Mberu1, T Wansor, H Sato, Y Nishikawa, W M Watkins.   

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Year:  1995        PMID: 8594689     DOI: 10.1016/0035-9203(95)90434-4

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


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  3 in total

1.  Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil.

Authors:  D A Fidock; T E Wellems
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

Review 2.  Application of pharmacogenomics to malaria: a holistic approach for successful chemotherapy.

Authors:  Rajeev K Mehlotra; Cara N Henry-Halldin; Peter A Zimmerman
Journal:  Pharmacogenomics       Date:  2009-03       Impact factor: 2.533

3.  Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone.

Authors:  Tina S Skinner-Adams; John H Ryan; Katherine T Andrews; Gillian M Fisher; Andrew G Riches; Oliver E Hutt; Karen E Jarvis; Tony Wilson; Mark von Itzstein; Pradeep Chopra; Yevgeniya Antonova-Koch; Stephan Meister; Elizabeth A Winzeler; Mary Clarke; David A Fidock; Jeremy N Burrows
Journal:  Commun Biol       Date:  2019-05-03
  3 in total

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