Literature DB >> 8594148

Agastaquinone, a new cytotoxic diterpenoid quinone from Agastache rugosa.

H K Lee1, S R Oh, J I Kim, J W Kim, C O Lee.   

Abstract

A new diterpenoid quinone, agastaquinone [1], was isolated from the roots of Agastache rugosa. An oxime derivative [2] of agastaquinone was prepared with hydroxylamine hydrochloride. The structure of agastaquinone [1] was established as 7-hydroxy-12-methoxy-20-norabieta-1,5(10),6,8,12-pentaene-3,11,14- trione by spectroscopic techniques. Compounds 1 and 2 showed nonspecific cytotoxic activities against several human cancer cell lines in vitro (A549, SK-OV-3, SK-MEL-2, XF498, and HCT15).

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Year:  1995        PMID： 8594148     DOI： 10.1021/np50125a011

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  Chemical constituents and coagulation activity of Agastache rugosa.

Authors:  Pengran Cao; Pingyao Xie; Xuebiao Wang; Jinmei Wang; Jinfeng Wei; Wen-Yi Kang
Journal:  BMC Complement Altern Med       Date:  2017-02-06       Impact factor: 3.659

2.  Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of Horminum pyrenaicum in Human PBMC.

Authors:  K Becker; S Schwaiger; B Waltenberger; D Fuchs; C K Pezzei; H Schennach; H Stuppner; J M Gostner
Journal:  Oxid Med Cell Longev       Date:  2018-01-14       Impact factor: 6.543

3.  Changes in Human Electroencephalographic Activity in Response to Agastache rugosa Essential Oil Exposure.

Authors:  Minji Hong; Hyejeong Jang; Sela Bo; Minju Kim; Ponnuvel Deepa; Jiyea Park; Kandhasamy Sowndhararajan; Songmun Kim
Journal:  Behav Sci (Basel)       Date:  2022-07-15

Review 4.  Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae).

Authors:  Sylwia Zielińska; Adam Matkowski
Journal:  Phytochem Rev       Date:  2014-04-03       Impact factor: 5.374
  4 in total

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