| Literature DB >> 8590597 |
J Y VanDenburg1, P N McFadden.
Abstract
Two nonionic-detergent-insoluble proteins are induced early in the nerve growth factor (NGF)-induced neuronal differentiation of PC12 cells. The pools of these two proteins then disappear from the insoluble fraction after a few days of continued exposure of the cells to NGF. The methylation-inhibiting drug adenosine dialdehyde blocks the disappearance of these insoluble proteins, implicating a methylation-dependent step in the pathway that regulates the fate of these proteins.Entities:
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Year: 1995 PMID: 8590597 DOI: 10.1007/bf01886786
Source DB: PubMed Journal: J Protein Chem ISSN: 0277-8033