| Literature DB >> 8588866 |
I K Lee1, C J Kim, K S Song, H M Kim, H Koshino, M Uramoto, I D Yoo.
Abstract
Three new dihydroflavonols, gericudranins A-C were isolated from the stem bark of Cudrania tricuspidata. They were identified as 6,8-di-p-hydroxybenzyltaxifolin, 8-p-hydroxybenzyltaxifolin and 6-p-hydroxybenzyltaxifolin, respectively, by means of spectral studies. These compounds were cytotoxic to human tumor cell lines, such as CRL 1579 (skin), LOX-IMVI (skin), MOLT-4F (leukemia), KM12 (colon) and UO-31 (renal) in culture, with ED50 values of 2.7-31.3 micrograms ml-1.Entities:
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Year: 1996 PMID： 8588866 DOI： 10.1016/0031-9422(95)00609-5
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072