Literature DB >> 8588752

[Smoking habits in chronic schizophrenics].

K Fukui1, T Kobayashi, S Hayakawa, E Koga, S Okazaki, Y Kawashima, F Kawakami, Y Fukui, N Tani, A Kato.   

Abstract

The smoking habits of 48 chronic schizophrenics who were inpatients of private psychiatric were examined. Subjects were divided into three groups; non-smokers, moderate smokers and heavy smokers, and tested by Fagerstrom's Tolerance Questionnaire (FTQ) as a tobacco dependence evaluation, and Bender Gestalt Test (BGT) and Benton Visual Retention Test (BVRT) as a neuropsychological battery. In addition, we used the Scales for the Assessment of Negative Symptoms (SANS) to evaluate the degree of schizophrenic negative symptoms, confirming the correlation between SANS score and the amount of nicotine intake or FTQ item. From the results of FTQ scores and their correlation with SANS scores, the amount of nicotine intake was significantly related to the severity of schizophrenic negative symptoms including affective blunting, poverty of thinking and attention impairment. BGT and BVRT showed disturbances in visual-motor gestalt function, and attention and memory, in chronic schizophrenics who smoked, especially in heavy smokers. These results suggest that smoking behavior in chronic schizophrenics might increase the individual vigilance against negative symptoms, from the perspective of self-medication.

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Year:  1995        PMID: 8588752

Source DB:  PubMed          Journal:  Arukoru Kenkyuto Yakubutsu Ison        ISSN: 0389-4118


  2 in total

1.  Varenicline as a smoking cessation aid in schizophrenia: effects on smoking behavior and reward sensitivity.

Authors:  Sunny J Dutra; Luke E Stoeckel; Sara V Carlini; Diego A Pizzagalli; A Eden Evins
Journal:  Psychopharmacology (Berl)       Date:  2011-06-22       Impact factor: 4.530

2.  In vivo evidence for β2 nicotinic acetylcholine receptor subunit upregulation in smokers as compared with nonsmokers with schizophrenia.

Authors:  Irina Esterlis; Mohini Ranganathan; Frederic Bois; Brian Pittman; Marina R Picciotto; Lara Shearer; Alan Anticevic; Jon Carlson; Mark J Niciu; Kelly P Cosgrove; D Cyril D'Souza
Journal:  Biol Psychiatry       Date:  2013-11-13       Impact factor: 13.382

  2 in total

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