Literature DB >> 8586564

Calbindin D28k in the olivocerebellar projection. A light and electron microscope study.

A L Scotti1.   

Abstract

The distribution of the calcium binding protein calbindin D28k (CaBP) in the rat and gerbil olivocerebellar system was compared and an ultrastructural analysis of the inferior olive and cerebellum was performed in the gerbil. CaBP is present in the perikarya and dendritic arborisations of inferior olivary neurons. The olivocerebellar projection in the inferior cerebellar peduncle stains for CaBP. CaBP is also contained in the terminal branches of the olivocerebellar projection: the climbing fibres in the inner molecular layer of the cerebellum. Thus CaBP is a reliable marker for the whole olivocerebellar projection in adult rodents. Presence of the calcium binding protein CaBP in inferior olivary neurons may influence the different calcium conductances of their dendritic, somatic and terminal compartments responsible for the physiological properties of these nerve cells.

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Year:  1995        PMID： 8586564      PMCID： PMC1167468     

Source DB:  PubMed          Journal:  J Anat        ISSN： 0021-8782            Impact factor:   2.610


  44 in total

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