Literature DB >> 8586444

The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2.

H U Weier1, C X George, K M Greulich, C E Samuel.   

Abstract

The interferon-inducible double-stranded RNA-specific adenosine deaminase is an RNA-modifying enzyme implicated in the generation of biased hypermutations viral RNAs and the site-selective editing of mammalian mRNAs of neural origin. The gene for the dsRNA-specific adenosine deaminase has been mapped by fluorescence in situ hybridization (FISH) of genomic clones to a single locus on human chromosome 1 bands q21.1-21.2. Simultaneous multicolor FISH including lambda clones and yeast artificial chromosomes showed a localization of the gene in band 1q21 centromeric of D1S1705.

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Year:  1995        PMID: 8586444     DOI: 10.1006/geno.1995.0034

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  23 in total

1.  Patient-specific probes for preimplantation genetic diagnosis of structural and numerical aberrations in interphase cells.

Authors:  H U Weier; S Munné; J Fung
Journal:  J Assist Reprod Genet       Date:  1999-04       Impact factor: 3.412

Review 2.  Adenosine deaminases acting on RNA, RNA editing, and interferon action.

Authors:  Cyril X George; Zhenji Gan; Yong Liu; Charles E Samuel
Journal:  J Interferon Cytokine Res       Date:  2010-12-23       Impact factor: 2.607

Review 3.  ADARs: viruses and innate immunity.

Authors:  Charles E Samuel
Journal:  Curr Top Microbiol Immunol       Date:  2012       Impact factor: 4.291

4.  Unraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomics.

Authors:  Jisheng Guo; Xiaoyue Wang; Xin Lü; Ruirui Jing; Junqiang Li; CuiLing Li; Daoguang Wang; Baibin Bi; Xinjun Chen; Fengqin Wang; Shengnan Sun; Jing Gong; Kazem M Azadzoi; Jing-Hua Yang
Journal:  Cell Cycle       Date:  2016-04-22       Impact factor: 4.534

Review 5.  Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA-triggered innate immune responses.

Authors:  Charles E Samuel
Journal:  J Biol Chem       Date:  2019-02-01       Impact factor: 5.157

6.  Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library.

Authors:  I Marenholz; M Zirra; D F Fischer; C Backendorf; A Ziegler; D Mischke
Journal:  Genome Res       Date:  2001-03       Impact factor: 9.043

7.  Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions.

Authors:  Jennifer L Hood; Michael V Morabito; Charles R Martinez; James A Gilbert; Elizabeth A Ferrick; Gregory D Ayers; James D Chappell; Terence S Dermody; Ronald B Emeson
Journal:  Mol Cell Neurosci       Date:  2014-06-04       Impact factor: 4.314

8.  Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible.

Authors:  C X George; C E Samuel
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-13       Impact factor: 11.205

Review 9.  An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).

Authors:  Cyril X George; Lijo John; Charles E Samuel
Journal:  J Interferon Cytokine Res       Date:  2014-06       Impact factor: 2.607

10.  RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR.

Authors:  Ann M Toth; Zhiqun Li; Roberto Cattaneo; Charles E Samuel
Journal:  J Biol Chem       Date:  2009-08-25       Impact factor: 5.157

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