Literature DB >> 8586379

Double cancer in different hepatic lobes: hepatocellular and cholangiocellular carcinoma.

S Ohwada1, O Yoshihiro, S Iwazaki, Y Tanahashi, T Sawada, I Takeyoshi, Y Kawashima, S Nakaura, Y Iino, Y Morishita.   

Abstract

BACKGROUND/AIM: Hepatic tumors with elements of both hepatocellular and cholangiocellular carcinoma are occasionally encountered; however, the independent and simultaneous occurrence of different epithelial malignant tumors in different lobes is rare. This is a case report of resected double cancer in different lobes of the liver.
MATERIALS AND METHODS: A 73 year old Japanese man, with hepatic mass and a history of peritonitis and hepatitis, underwent laparotomy and hepatic resection of the posterior inferior and the left lateral segment, and cholecystectomy for cholecystlithiasis with left-sided gallbladder at our hospital in 1991.
RESULTS: The tumor, located in the posterior inferior segment, a yellow-white, round, highly circumscribed mass with a thick capsule, was about 9.0 by 8.0 cm in size. The other tumor located in the left lateral segment, grayish-white on the cut section, was approximately 5.0 by 4.0 cm.
CONCLUSION: In our case, it is unlikely the tumor in the right lobe metastasized to the left lobe and transformed into a different type. The two tumors showed clearly different microscopic features. Improved imaging will increase the frequency and number of double cancer diagnosis. This additional data may shed light on the pathogenesis and etiology of double cancer.

Entities:  

Mesh:

Year:  1995        PMID: 8586379

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  5 in total

1.  Synchronous double primary malignant tumor of the gallbladder and liver: a case report.

Authors:  Ji Won Kim; Jae Woong Han; So Young Jung; Jae Pil Jung; Jeong Won Kim
Journal:  World J Surg Oncol       Date:  2011-08-03       Impact factor: 2.754

2.  Synchronous development of HCC and CCC in the same subsegment of the liver in a patient with type C liver cirrhosis.

Authors:  Takuya Watanabe; Jun Sakata; Takashi Ishikawa; Yoshio Shirai; Takeyasu Suda; Haruka Hirono; Katsuhiko Hasegawa; Kenji Soga; Koichi Shibasaki; Yukifumi Saito; Hajime Umezu
Journal:  World J Hepatol       Date:  2009-10-31

3.  Perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis with hepatocellular carcinoma.

Authors:  Takahiko Fujii; Yoh Zen; Yasuni Nakanuma
Journal:  J Gastroenterol       Date:  2007-08-24       Impact factor: 7.527

4.  A case report of synchronous double primary liver cancers combined with early gastric cancer.

Authors:  Jae Young Chang; Byung-Ho Kim; Sung Wha Hong; Youn Wha Kim; Joo Hyeong Oh
Journal:  Korean J Intern Med       Date:  2003-06       Impact factor: 2.884

5.  Synchronous double primary malignancies of the liver and kidney: A case report.

Authors:  Jun-Jun Sun; Tian-Bao Yang; Yan-Hui Yang; Wei-Feng Liu; Jun-Xin Song
Journal:  Oncol Lett       Date:  2016-02-08       Impact factor: 2.967

  5 in total

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