| Literature DB >> 8586194 |
H K Kuramitsu1, M Smorawinska, Y J Nakano, A Shimamura, M Lis.
Abstract
Glucan synthesis by Streptococcus mutans GS-5 has been analyzed by examining the regulation of expression and structure-function relationships of the glucosyltransferases. Primer extension analysis of the gtf genes has identified the putative promoter sequences for these genes and indicated that the -10 sequences are similar to the Escherichia coli consensus sequence. Site-directed mutagenesis as well as deletion analysis of the enzymes have identified amino acid residues as well as functional domains which play important roles in glucan synthesis.Entities:
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Year: 1995 PMID： 8586194
Source DB: PubMed Journal: Dev Biol Stand ISSN： 0301-5149