Literature DB >> 8584937

Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA.

K C Keiler1, P R Waller, R T Sauer.   

Abstract

Variants of lambda repressor and cytochrome b562 translated from messenger RNAs without stop codons were modified by carboxyl terminal addition of an ssrA-encoded peptide tag and subsequently degraded by carboxyl terminal-specific proteases present in both the cytoplasm and periplasm of Escherichia coli. The tag appears to be added to the carboxyl terminus of the nascent polypeptide chain by cotranslational switching of the ribosome from the damaged messenger RNA to ssrA RNA.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8584937     DOI： 10.1126/science.271.5251.990

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  425 in total

1.  A mutant HemA protein with positive charge close to the N terminus is stabilized against heme-regulated proteolysis in Salmonella typhimurium.

Authors:  L Wang; S Wilson; T Elliott
Journal:  J Bacteriol       Date:  1999-10       Impact factor: 3.490

2.  tmRDB (tmRNA database).

Authors:  C Zwieb; J Wower
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

3.  The tmRNA website.

Authors:  K P Williams
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

4.  tmRDB (tmRNA database).

Authors:  B Knudsen; J Wower; C Zwieb; J Gorodkin
Journal:  Nucleic Acids Res       Date:  2001-01-01       Impact factor: 16.971

5.  ClpA mediates directional translocation of substrate proteins into the ClpP protease.

Authors:  B G Reid; W A Fenton; A L Horwich; E U Weber-Ban
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-20       Impact factor: 11.205

6.  Phylogenetic analysis of tmRNA genes within a bacterial subgroup reveals a specific structural signature.

Authors:  B Felden; C Massire; E Westhof; J F Atkins; R F Gesteland
Journal:  Nucleic Acids Res       Date:  2001-04-01       Impact factor: 16.971

7.  Here's the hook: similar substrate binding sites in the chaperone domains of Clp and Lon.

Authors:  S Wickner; M R Maurizi
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

Review 8.  Chaperone rings in protein folding and degradation.

Authors:  A L Horwich; E U Weber-Ban; D Finley
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 9.  Mapping the bacterial cell architecture into the chromosome.

Authors:  A Danchin; P Guerdoux-Jamet; I Moszer; P Nitschké
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-02-29       Impact factor: 6.237

10.  The thylakoid FtsH protease plays a role in the light-induced turnover of the photosystem II D1 protein.

Authors:  M Lindahl; C Spetea; T Hundal; A B Oppenheim; Z Adam; B Andersson
Journal:  Plant Cell       Date:  2000-03       Impact factor: 11.277
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.