Literature DB >> 8583997

Advances in chemotherapy for brain tumors.

C A Conrad1, V P Milosavljevic, W K Yung.   

Abstract

Malignant brain tumors, particularly those of glial origin, carry a dismal prognosis despite decades of therapeutic maneuvers. Surgery and radiotherapy have not been curative, and adjunctive chemotherapy has resulted only in modest increases in survival. This article discusses the current status of chemotherapy, the problems encountered with the interpretation of chemotherapeutic trials, and some of the new approaches currently being evaluated.

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Year:  1995        PMID： 8583997

Source DB:  PubMed          Journal:  Neurol Clin        ISSN： 0733-8619            Impact factor:   3.806


  6 in total

1.  Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.

Authors:  Manuel Nieto-Sampedro; Beatriz Valle-Argos; Diego Gómez-Nicola; Alfonso Fernández-Mayoralas; Manuel Nieto-Díaz
Journal:  Clin Med Insights Oncol       Date:  2011-09-21

2.  Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.

Authors:  Wen-bin Zhang; Zhuo Wang; Fei Shu; Yong-hua Jin; Hong-yi Liu; Qiu-juan Wang; Yong Yang
Journal:  J Biol Chem       Date:  2010-09-29       Impact factor: 5.157

Review 3.  Recognition and management of gliomas.

Authors:  S E Kaba; A P Kyritsis
Journal:  Drugs       Date:  1997-02       Impact factor: 9.546

4.  Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11.

Authors:  Tracy T Batchelor; Mark R Gilbert; Jeffrey G Supko; Kathryn A Carson; Louis B Nabors; Stuart A Grossman; Glenn J Lesser; Tom Mikkelsen; Surasak Phuphanich
Journal:  Neuro Oncol       Date:  2004-01       Impact factor: 12.300

5.  CB2 Receptor Agonist JWH133 Activates AMPK to Inhibit Growth of C6 Glioma Cells.

Authors:  Feng Wang; Jing Wang; Tong Zhao; Yi Zhang; Qian Li
Journal:  Open Life Sci       Date:  2019-07-22       Impact factor: 0.938

6.  Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor.

Authors:  Barbara Costa; Sara Bendinelli; Pamela Gabelloni; Eleonora Da Pozzo; Simona Daniele; Fabrizio Scatena; Renato Vanacore; Pietro Campiglia; Alessia Bertamino; Isabel Gomez-Monterrey; Daniela Sorriento; Carmine Del Giudice; Guido Iaccarino; Ettore Novellino; Claudia Martini
Journal:  PLoS One       Date:  2013-08-19       Impact factor: 3.240
  6 in total

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