Literature DB >> 8579832

Epinigericin toxicity towards Tetrahymena pyriformis GL; changes in cell volume and intracellular pH.

M Bamdad1, L David, C A Grolière.   

Abstract

A study of the toxicity of epinigericin, an antibiotic ionophor, towards the ciliate Tetrahymena pyriformis showed that this molecule stopped cell division, increased cell volume and led to a more basic intracellular pH. The action of epinigericin was probably linked to its function as an ionophor. The ionic selectivity of this molecule is still not known. The raising of the intracellular pH of ciliates by this antibiotic may be linked to its toxic action and its iontransport mechanism in Tetrahymena.

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Year:  1995        PMID： 8579832     DOI： 10.1007/bf00164503

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN： 0175-7598            Impact factor:   4.813


  6 in total

1.  In vitro study of the effect of different ionophore antibiotics and of certain derivatives on rumen fermentation and on protein nitrogen degradation.

Authors:  M C Hillaire; J P Jouany; C Gaboyard; G Jeminet
Journal:  Reprod Nutr Dev       Date:  1989

2.  Study by NMR of the mode of action of monensin on Streptococcus faecalis de-energized and energized cells.

Authors:  A M Delort; G Dauphin; J Guyot; G Jeminet
Journal:  Biochim Biophys Acta       Date:  1989-09-04

3.  Effects of dimethyl sulfoxide on Tetrahymena pyriformis GL. Fine structural changes and their reversibility.

Authors:  J R Nilsson
Journal:  J Protozool       Date:  1977-05

4.  Microbial conversion of lonophorous antibiotic nigericin by the ciliate Tetrahymena pyriformis.

Authors:  M Bamdad; C A Grolière; J Dupy-Blanc; A Cuer; L David; J C Tabet
Journal:  Eur J Protistol       Date:  2011-11-08       Impact factor: 3.020

5.  Change in intracellular pH in Tetrahymena pyriformis GL in relation to the toxicity level of the lonophorous antibiotic nigericin.

Authors:  M Bamdad; C A Grolière; J Dupy-Blanc; L David; M Gendraud
Journal:  Eur J Protistol       Date:  2011-11-02       Impact factor: 3.020

6.  [Not Available].

Authors:  J Dupy-Blanc; C A Grolière; R Berrada; L David
Journal:  Eur J Protistol       Date:  2011-11-02       Impact factor: 3.020
  6 in total
  1 in total

1.  Loss of the Acetate Switch in Vibrio vulnificus Enhances Predation Defense against Tetrahymena pyriformis.

Authors:  Viduthalai Rasheedkhan Regina; Parisa Noorian; Clarence Bo Wen Sim; Florentin Constancias; Eganathan Kaliyamoorthy; Sean C Booth; Gustavo Espinoza-Vergara; Scott A Rice; Diane McDougald
Journal:  Appl Environ Microbiol       Date:  2021-11-03       Impact factor: 4.792
  1 in total

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