| Literature DB >> 857899 |
M Astruc, C Tabacik, B Descomps, A C de Paulet.
Abstract
Squalene epoxidase and oxidosqualene lanosterol-cyclase activities have been studied in normal mammalian cholesterogenic and non-cholesterogenic tissues. This paper describes the kinetic conditions of measurement of these two enzymatic acitivities and their results. Oxidosqualene lanosterol-cyclase is a widespread enzyme, present in all cholesterogenic and non-cholesterogenic tissues. However, the level of squalene epoxidase is very low in non-cholesterogenic tissues. However, the level of squalene epoxidase is very low in non-cholesterogenic tissues. The effects of subcellular fractionizing and of the physico-chemical state of squalene incubated in vitro on squalene epoxidase activity are discussed.Entities:
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Year: 1977 PMID： 857899 DOI： 10.1016/0005-2760(77)90056-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002