Literature DB >> 8577505

Localized Langerhans cell histiocytosis of bone: treatment and follow- up in children.

M Libicher1, T Roeren, J Tröger.   

Abstract

We report a case of Langerhans cell histiocytosis (LCH) involving the right scapula in a 4-year-old child. Because of progressive shoulder pain and immobility methylprednisolone was injected directly into the lesion under computed tomography (CT) guidance. Follow-up studies with magnetic resonance imaging (MRI) and ultrasound (US) revealed continuous ossification of the osteolytic lesion with healing after 6 months. Plain films and CT confirmed the healing process. We consider intralesional corticoid instillation a safe method when performed under CT guidance. For initial evaluation and follow-up, MRI and US yielded reliable results in comparison to plain films and CT, thus helping to reduce the radiation dosage in children.

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Year:  1995        PMID: 8577505

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  2 in total

Review 1.  Langerhans' cell histiocytosis: pathology, imaging and treatment of skeletal involvement.

Authors:  E Michel Azouz; Gaurav Saigal; Maria M Rodriguez; Antonello Podda
Journal:  Pediatr Radiol       Date:  2004-07-28

2.  Multifocal Langerhans cell histiocytosis in an adult with a pathological fracture of the mandible and spontaneous malunion: A case report.

Authors:  Sailang Shi; Yanming Liu; Tao Fu; Xiuzhen Li; Shifang Zhao
Journal:  Oncol Lett       Date:  2014-06-20       Impact factor: 2.967

  2 in total

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