Literature DB >> 8577192

Lumbar and caudal epidural corticosteroid injections.

K C Spaccarelli1.   

Abstract

OBJECTIVE: To describe the indications, rationale, techniques, alternatives, contraindications, complications, and efficacy of lumbar and caudal epidural corticosteroid injections.
DESIGN: Case reports and retrospective and prospective studies were extensively reviewed to provide detailed descriptions of the clinical features of lumbar and caudal epidural corticosteroid injections.
RESULTS: Epidural corticosteroid injections are commonly requested treatments for patients with various low-back or lower-extremity pain syndromes (or both). Most of the reports on the use of this type of treatment are retrospective and noncontrolled. These studies indicate benefit; however, the prospective controlled studies provide varied results about the efficacy of lumbar and caudal epidural corticosteroid injections.
CONCLUSION: A thorough analysis of the few available controlled studies and their limitations indicates that this treatment is probably efficacious for patients with certain lower-extremity radicular pain syndromes when intermediate-term (2 weeks to 3 months) results are assessed after injection. More studies are needed to elucidate further the most beneficial candidates and techniques.

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Year:  1996        PMID: 8577192     DOI: 10.4065/71.2.169

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  11 in total

Review 1.  Intraspinal steroids: history, efficacy, accidentality, and controversy with review of United States Food and Drug Administration reports.

Authors:  D A Nelson; W M Landau
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-04       Impact factor: 10.154

2.  Efficacy of Epidural Steroid Injection in Management of Lumbar Prolapsed Intervertebral Disc: A Comparison of Caudal, Transforaminal and Interlaminar Routes.

Authors:  Ritesh Arvind Pandey
Journal:  J Clin Diagn Res       Date:  2016-07-01

3.  Metabolic and endocrinal effects of epidural glucocorticoid injections.

Authors:  Anuntapon Chutatape; Mahesh Menon; Stephanie Man Chung Fook-Chong; Jane Mary George
Journal:  Singapore Med J       Date:  2018-11-07       Impact factor: 1.858

4.  Activation of GRs-Akt-nNOs-NR2B signaling pathway by second dose GR agonist contributes to exacerbated hyperalgesia in a rat model of radicular pain.

Authors:  Jing Zhang; Wei Zhang; Yu'e Sun; Yue Liu; Lihua Song; Zhengliang Ma; Xiaoping Gu
Journal:  Mol Biol Rep       Date:  2014-02-23       Impact factor: 2.316

5.  The Incidence of Lumbar Discectomy after Epidural Steroid Injections or Selective Nerve Root Blocks.

Authors:  William F Lavelle; Thomas Mroz; Isador Lieberman
Journal:  Int J Spine Surg       Date:  2015-04-29

6.  Injectable corticosteroid preparations: an embolic risk assessment by static and dynamic microscopic analysis.

Authors:  P J MacMahon; M J Shelly; D Scholz; S J Eustace; E C Kavanagh
Journal:  AJNR Am J Neuroradiol       Date:  2011-09-22       Impact factor: 3.825

7.  Arachnoiditis following caudal epidural injections for the lumbo-sacral radicular pain.

Authors:  Shashi Kumar Nanjayan; Girish Nanjunda Swamy; Sachin Yallappa; Rajendra Bommireddy
Journal:  Asian Spine J       Date:  2013-11-28

8.  Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients.

Authors:  Pascal Zufferey; Charly Bulliard; Gerald Gremion; Marial Saugy; Alexander So
Journal:  BMC Res Notes       Date:  2011-12-21

Review 9.  Epidural steroid injections in the management of low-back pain with radiculopathy: an update of their efficacy and safety.

Authors:  Michel Benoist; Philippe Boulu; Gilles Hayem
Journal:  Eur Spine J       Date:  2011-09-16       Impact factor: 3.134

10.  Epidural corticosteroid injections for sciatica: a randomised, double blind, controlled clinical trial.

Authors:  J-P Valat; B Giraudeau; S Rozenberg; P Goupille; P Bourgeois; V Micheau-Beaugendre; M Soubrier; S Richard; E Thomas
Journal:  Ann Rheum Dis       Date:  2003-07       Impact factor: 19.103

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