Literature DB >> 8575558

The history of cyclosporin A (Sandimmune) revisited: another point of view.

H F Stähelin.   

Abstract

The immunosuppressant cyclosporin A (Sandimmune) has become the first line treatment for preventing rejection of transplanted organs and for certain autoimmune diseases. The discovery of that drug and its preclinical development are described, and it is shown that most earlier accounts of the history of this compound are, in important respects, incorrect and misleading.

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Year:  1996        PMID： 8575558     DOI： 10.1007/bf01922409

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  43 in total

1.  [ON THE STRUCTURE OF VERRUCARINE A. VERRUCARINE AND RORIDINE, 5].

Authors:  J GUTZWILLER; C TAMM
Journal:  Helv Chim Acta       Date:  1965-01-02       Impact factor: 2.164

2.  [Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity].

Authors:  A Rüegger; M Kuhn; H Lichti; H R Loosli; R Huguenin; C Quiquerez; A von Wartburg
Journal:  Helv Chim Acta       Date:  1976       Impact factor: 2.164

3.  Inhibition of human lymphocyte transformation by the macrocyclic trichothecenes roridin A and verrucarin A.

Authors:  J J Pestka; J H Forsell
Journal:  Toxicol Lett       Date:  1988-06       Impact factor: 4.372

4.  [Isolation and structural clarification of chlamydocin].

Authors:  A Closse; R Huguenin
Journal:  Helv Chim Acta       Date:  1974-04-27       Impact factor: 2.164

5.  Immunosuppressive effect of a new antibiotic: ovalicin.

Authors:  S Lazary; H Stähelin
Journal:  Antibiot Chemother       Date:  1969

6.  Drug transforms transplant medicine.

Authors:  G Kolata
Journal:  Science       Date:  1983-07-01       Impact factor: 47.728

7.  Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide.

Authors:  H Stähelin; A Trippmacher
Journal:  Eur J Cancer       Date:  1974-12       Impact factor: 9.162

8.  Effects of cytochalasins on mammalian cells.

Authors:  S B Carter
Journal:  Nature       Date:  1967-01-21       Impact factor: 49.962

9.  Extensive prolongation of rabbit kidney allograft survival after short-term cyclosporin-A treatment.

Authors:  C J Green; A C Allison
Journal:  Lancet       Date:  1978-06-03       Impact factor: 79.321

10.  Phase II evaluation of anguidine (NSC 141537) in 5-day courses in colorectal adenocarcinoma. A Southeastern Cancer Study Group Trial.

Authors:  P A DeSimone; F A Greco; H F Lessner; A Bartolucci
Journal:  Am J Clin Oncol       Date:  1986-06       Impact factor: 2.339
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  18 in total

Review 1.  Therapeutic drug monitoring of immunosuppressant drugs.

Authors:  A Johnston; D W Holt
Journal:  Br J Clin Pharmacol       Date:  1999-04       Impact factor: 4.335

Review 2.  A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya).

Authors:  Jerold Chun; Volker Brinkmann
Journal:  Discov Med       Date:  2011-09       Impact factor: 2.970

Review 3.  Natural product discovery: past, present, and future.

Authors:  Leonard Katz; Richard H Baltz
Journal:  J Ind Microbiol Biotechnol       Date:  2016-01-06       Impact factor: 3.346

4.  Expanding the limits of isonitrile-mediated amidations: on the remarkable stereosubtleties of macrolactam formation from synthetic seco-cyclosporins.

Authors:  Xiangyang Wu; Jennifer L Stockdill; Peter K Park; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2012-01-17       Impact factor: 15.419

5.  Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set.

Authors:  Zachary Woodward; Peter Brooks; Bernadette Morris-Smith; Marianne Wallis; Steven M Ogbourne
Journal:  Pharm Res       Date:  2018-04-19       Impact factor: 4.200

Review 6.  Molecular aspects of cyclophilins mediating therapeutic actions of their ligands.

Authors:  Andrzej Galat; Jacqueline Bua
Journal:  Cell Mol Life Sci       Date:  2010-07-04       Impact factor: 9.261

Review 7.  Mouse models in bone marrow transplantation and adoptive cellular therapy.

Authors:  Caroline Arber; Malcolm K Brenner; Pavan Reddy
Journal:  Semin Hematol       Date:  2013-06-11       Impact factor: 3.851

8.  External evaluation of population pharmacokinetic models for ciclosporin in adult renal transplant recipients.

Authors:  Jun-Jun Mao; Zheng Jiao; Hwi-Yeol Yun; Chen-Yan Zhao; Han-Chao Chen; Xiao-Yan Qiu; Ming-Kang Zhong
Journal:  Br J Clin Pharmacol       Date:  2017-11-03       Impact factor: 4.335

9.  Expression of a synthetic Artemesia annua amorphadiene synthase in Aspergillus nidulans yields altered product distribution.

Authors:  David Lubertozzi; Jay D Keasling
Journal:  J Ind Microbiol Biotechnol       Date:  2008-07-24       Impact factor: 3.346

Review 10.  Mining the metabiome: identifying novel natural products from microbial communities.

Authors:  Aleksandr Milshteyn; Jessica S Schneider; Sean F Brady
Journal:  Chem Biol       Date:  2014-09-18
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