Literature DB >> 8574805

Diffuse bone marrow uptake [123I]MIBG in neuroblastoma: an "MIBG super scan" case report.

F Giammarile1, A L Olier, J Lumbroso.   

Abstract

We present the case of a 3-year-old child with neuroblastoma metastatic to the bone marrow. [123I]MIBG total body scintigraphy revealed a diffuse pattern of intense fixation throughout the skeleton. This was analogous to the "super scan" described with 99mTc-MDP bone scintigraphy when extensive metastatic or metabolic bone disease is present. Essentially, a high bone-to-soft tissue ratio was found without uptake in the liver, kidney and bladder, owing to a "steal" mechanism caused by the avid bone metastases.

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Year:  1995        PMID: 8574805

Source DB:  PubMed          Journal:  Q J Nucl Med        ISSN: 1125-0135


  2 in total

1.  The mIBG super scan.

Authors:  F Giammarile
Journal:  Pediatr Radiol       Date:  1997-02

2.  MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis.

Authors:  Gitta Bleeker; Berthe L van Eck-Smit; Koos H Zwinderman; Rogier Versteeg; Max M van Noesel; Boen L Kam; Gertjan J Kaspers; Annelies van Schie; Susan G Kreissman; Gregory Yanik; Barbara Hero; Matthias Schmidt; Geneviève Laureys; Bieke Lambert; Ingrid Øra; Johannes H Schulte; Huib N Caron; Godelieve A Tytgat
Journal:  Eur J Nucl Med Mol Imaging       Date:  2014-09-30       Impact factor: 9.236

  2 in total

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