Literature DB >> 8574575

Huntington's disease. Their loss is our gain?

W Feero1, E P Hoffman.   

Abstract

'Knockout' mice have been developed that lack the Huntington's disease gene, in an effort to gain insight into the disorder and into the pathophysiological effects of tri-nucleotide repeat expansion.

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Year:  1995        PMID： 8574575     DOI： 10.1016/s0960-9822(95)00244-2

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  2 in total

1.  Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease.

Authors:  Eduardo E Arteaga-Bracho; Maria Gulinello; Michael L Winchester; Nandini Pichamoorthy; Jenna R Petronglo; Alicia D Zambrano; Julio Inocencio; Chirstopher D De Jesus; Joseph O Louie; Solen Gokhan; Mark F Mehler; Aldrin E Molero
Journal:  Neurobiol Dis       Date:  2016-09-10       Impact factor: 5.996

2.  Abnormal Brain Development in Huntington' Disease Is Recapitulated in the zQ175 Knock-In Mouse Model.

Authors:  Chuangchuang Zhang; Qian Wu; Hongshuai Liu; Liam Cheng; Zhipeng Hou; Susumu Mori; Jun Hua; Christopher A Ross; Jiangyang Zhang; Peggy C Nopoulos; Wenzhen Duan
Journal:  Cereb Cortex Commun       Date:  2020-08-05
  2 in total

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