Literature DB >> 8574514

Animal models of protective immunity in tuberculosis to evaluate candidate vaccines.

J F Griffin1, C G Mackintosh, G S Buchan.   

Abstract

While the etiology of tuberculosis is well understood, the nature of the protective immune response to the causative mycobacteria has remained a mystery. There is an urgent need to define protective immunity critically, and to develop alternative animal models to evaluate the efficacy of new-generation vaccines against tuberculosis in a cost-effective way.

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Year:  1995        PMID： 8574514     DOI： 10.1016/s0966-842x(00)88994-5

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

1.  Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with Mycobacterium bovis or vaccination with killed, but not live, BCG.

Authors:  S Hook; F Griffin; C Mackintosh; G Buchan
Journal:  Immunology       Date:  1996-06       Impact factor: 7.397

2.  Experimental infection model for Johne's disease in sheep.

Authors:  D J Begg; R O'brien; C G Mackintosh; J F T Griffin
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

3.  An in vivo comparison of bacillus Calmette-Guérin (BCG) and cytokine-secreting BCG vaccines.

Authors:  L Slobbe; E Lockhart; M A O'Donnell; C MacKintosh; G De Lisle; G Buchan
Journal:  Immunology       Date:  1999-04       Impact factor: 7.397

4.  Genetic resistance to experimental infection with Mycobacterium bovis in red deer (Cervus elaphus).

Authors:  C G Mackintosh; T Qureshi; K Waldrup; R E Labes; K G Dodds; J F Griffin
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

5.  Immunological and molecular characterization of susceptibility in relationship to bacterial strain differences in Mycobacterium avium subsp. paratuberculosis infection in the red deer (Cervus elaphus).

Authors:  R O'Brien; C G Mackintosh; D Bakker; M Kopecna; I Pavlik; J F T Griffin
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

6.  Mycobacterium bovis-infected cervine alveolar macrophages secrete lymphoreactive lipid antigens.

Authors:  F E Aldwell; B L Dicker; F M da Silva Tatley; M F Cross; S Liggett; C G Mackintosh; J F Griffin
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

7.  A model of bovine tuberculosis control in domesticated cattle herds.

Authors:  R R Kao; M G Roberts; T J Ryan
Journal:  Proc Biol Sci       Date:  1997-07-22       Impact factor: 5.349

Review 8.  Zoonotic tuberculosis due to Mycobacterium bovis in developing countries.

Authors:  O Cosivi; J M Grange; C J Daborn; M C Raviglione; T Fujikura; D Cousins; R A Robinson; H F Huchzermeyer; I de Kantor; F X Meslin
Journal:  Emerg Infect Dis       Date:  1998 Jan-Mar       Impact factor: 6.883

9.  Stimulation of neutrophil granulocytes with Mycobacterium bovis bacillus Calmette-Guérin induces changes in phenotype and gene expression and inhibits spontaneous apoptosis.

Authors:  Henrik Suttmann; Nadine Lehan; Andreas Böhle; Sven Brandau
Journal:  Infect Immun       Date:  2003-08       Impact factor: 3.441

10.  Investigation of the role of CD8+ T cells in bovine tuberculosis in vivo.

Authors:  B Villarreal-Ramos; M McAulay; V Chance; M Martin; J Morgan; C J Howard
Journal:  Infect Immun       Date:  2003-08       Impact factor: 3.441
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