Literature DB >> 8572971

An improved left ventricular cannula for chronic dynamic blood pump support.

J F Antaki1, T J Dennis, H Konishi, M E Brown, T R Maher, J P Tomczak, J P Kerrigan, R L Kormos.   

Abstract

Ventricular unloading with dynamic blood pumps can be markedly affected by the geometry of the cannula tip within the ventricular chamber. Due to the ability of these pumps to develop significant negative inflow pressure, existing cannula tips designed for passively filling blood pumps can be predisposed to inflow occlusion by intraventricular anatomic structures. A novel "trumpet" mouth cannula was constructed to overcome this limiting problem. This design was based on two criteria: to provide additional stenting to the ventricular apex, and to assure placement of the tip opening relative to the endocardial surface. This prototype cannula was evaluated in vivo against conventional caged, blunt, and tapered designs to assess anatomic and hemodynamic interaction within the ventricular apex. Post mortem examination revealed the inflow tract to be devoid of myocardial obstruction in all cases. These initial studies indicate that a trumpet mouth cannula can provide satisfactory hemodynamic performance required by dynamic blood pumps.

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Year:  1995        PMID: 8572971     DOI: 10.1111/j.1525-1594.1995.tb02400.x

Source DB:  PubMed          Journal:  Artif Organs        ISSN: 0160-564X            Impact factor:   3.094


  3 in total

1.  In-vitro Evaluation of Ventricular Cannulation for Rotodynamic Cardiac Assist Devices.

Authors:  Timothy N Bachman; Jay K Bhama; Josiah Verkaik; Stijn Vandenberghe; Robert L Kormos; James F Antaki
Journal:  Cardiovasc Eng Technol       Date:  2011-09       Impact factor: 2.495

2.  Numerical prediction of thrombus risk in an anatomically dilated left ventricle: the effect of inflow cannula designs.

Authors:  Sam Liao; Benjamin Simpson; Michael Neidlin; Tim A S Kaufmann; Zhiyong Li; Maria A Woodruff; Shaun D Gregory
Journal:  Biomed Eng Online       Date:  2016-12-28       Impact factor: 2.819

3.  Numerical investigation of the effect of cannula placement on thrombosis.

Authors:  ChiWei Ong; Socrates Dokos; BeeTing Chan; Einly Lim; Amr Al Abed; Noor Azuan Bin Abu Osman; Suhaini Kadiman; Nigel H Lovell
Journal:  Theor Biol Med Model       Date:  2013-05-16       Impact factor: 2.432

  3 in total

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