Literature DB >> 857167

Circadian changes of the duration of action of local anaesthetic agents.

A Reinberg, M A Reinberg.   

Abstract

A statistically significant circadian rhythm of the duration of local anaesthesia produced by lidocaine and betoxycaine was found in both human skin and teeth. In adult subjects with diurnal activity and nocturnal rest the longest duration was found around 15.00 (3 p.m.) with a large peak-trough difference amounting to more than 100% of the 24 h mean. Such chronopharmacologic rhythm might be related to circadian rhythms in catecholamine secretion and/or in circadian changes of cell membrane properties.

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Year:  1977        PMID： 857167     DOI： 10.1007/BF00499924

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  8 in total

1.  Circadian variation of intercompartmental potassium fluxes in man.

Authors:  M C Moore Ede; M F Brennan; M R Ball
Journal:  J Appl Physiol       Date:  1975-01       Impact factor: 3.531

2.  Age and catecholamine rhythms.

Authors:  G C Descovich; N Montalbetti; J F Kühl; S Rimondi; F Halberg; C Ceredi
Journal:  Chronobiologia       Date:  1974 Apr-Jun

3.  Membrane model for the circadian clock.

Authors:  D Njus; F M Sulzman; J W Hastings
Journal:  Nature       Date:  1974-03-08       Impact factor: 49.962

4.  [Circadian rhythm of pulse, arterial blood pressure, urinary excretions of 17-hydroxycorticosteroids catecholamines and potassium in healthy adult humans active and during rest].

Authors:  A Reinberg; J Ghata; F Halberg; P Gervais; C Abulker; J Dupont; C Gaudeau
Journal:  Ann Endocrinol (Paris)       Date:  1970 Mar-Apr       Impact factor: 2.478

5.  Modes of action of local anesthetics in nerve and muscle in relation to their uptake and distribution.

Authors:  C P Blanchi; G E Strobel
Journal:  Trans N Y Acad Sci       Date:  1968-06

Review 6.  Chronopharmacology in man.

Authors:  A Reinberg
Journal:  Chronobiologia       Date:  1974-09

Review 7.  Circadian chronopharmacology.

Authors:  A Reinberg; F Halberg
Journal:  Annu Rev Pharmacol       Date:  1971       Impact factor: 13.820

8.  [Circadian variations of the effects of ethanol and of blood ethanol values in the healthy adult man. Chronopharmacological study].

Authors:  A Reinberg; J Clench; N Aymard; M Galliot; R Bourdon; P Gervais; C Abulker; J Dupont
Journal:  J Physiol (Paris)       Date:  1975
  8 in total
  5 in total

Review 1.  Therapeutic drug monitoring in the neonate and paediatric age group. Problems and clinical pharmacokinetic implications.

Authors:  J T Gilman
Journal:  Clin Pharmacokinet       Date:  1990-07       Impact factor: 6.447

Review 2.  Circadian changes of drug disposition in man.

Authors:  A Reinberg; M H Smolensky
Journal:  Clin Pharmacokinet       Date:  1982 Sep-Oct       Impact factor: 6.447

3.  Circadian changes in the bioavailability and effects of indomethacin in healthy subjects.

Authors:  J Clench; A Reinberg; Z Dziewanowska; J Ghata; M Smolensky
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

Review 4.  Circadian rhythms in anesthesia and critical care medicine: potential importance of circadian disruptions.

Authors:  Jason Brainard; Merit Gobel; Karsten Bartels; Benjamin Scott; Michael Koeppen; Tobias Eckle
Journal:  Semin Cardiothorac Vasc Anesth       Date:  2014-10-07

5.  Effect of the hour of administration on the pharmacokinetics of lidocaine in the rat.

Authors:  B Bruguerolle; M Valli; L Bouyard; G Jadot; P Bouyard
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1983 Jul-Sep       Impact factor: 2.441
  5 in total

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