Effects of nonuniform insonation by catheter-tipped Doppler transducers on velocity estimation.

Studies of the coronary arteries using intravascular Doppler catheters have frequently been performed to assess the local circulation in various clinical situations. The parameters which are correlated with clinical observations are usually calculated from the intensity weighted mean velocity (IWMV) or the maximum velocity extracted from the Doppler power spectrum. It is known that these estimates are affected by nonuniform insonation of the blood vessel by the ultrasonic beam. The sample volume of a commercially available Doppler catheter has been theoretically and experimentally studied, and the effects of the nonuniform sampling of the vessel by the ultrasound beam examined. The results show that the velocity estimates are dramatically affected by both the position of the catheter within the artery, and the blood velocity profile. It is concluded that the maximum velocity estimator is more reliable than the IWMV estimator, but that results obtained with this estimator must also be treated with extreme caution.