B B Johansson1. 1. Department of Neurology, Lund University Hospital, Sweden. barbro.johansson@neurol.lu.se
Abstract
BACKGROUND AND PURPOSE: The aim was to determine whether a delayed transfer to an enriched environment improves outcome after focal brain ischemia. METHODS: Performance on a rotating pole, prehensile traction, limb placement, and postural reflexes were tested in 15 spontaneously hypertensive rats housed in standard laboratory cages for 2 weeks after middle cerebral artery ligation. Seven of the 15 rats were then transferred to an enriched environment, and the two groups were tested 1, 3, and 5 weeks later. RESULTS: The enriched environment significantly improved pole performance, prehensile traction, and limb placement. CONCLUSIONS: Delayed postoperative environmental enrichment improves outcome in experimental stroke.
BACKGROUND AND PURPOSE: The aim was to determine whether a delayed transfer to an enriched environment improves outcome after focal brain ischemia. METHODS: Performance on a rotating pole, prehensile traction, limb placement, and postural reflexes were tested in 15 spontaneously hypertensiverats housed in standard laboratory cages for 2 weeks after middle cerebral artery ligation. Seven of the 15 rats were then transferred to an enriched environment, and the two groups were tested 1, 3, and 5 weeks later. RESULTS: The enriched environment significantly improved pole performance, prehensile traction, and limb placement. CONCLUSIONS: Delayed postoperative environmental enrichment improves outcome in experimental stroke.
Authors: Samuel S Shin; James W Bales; Hong Q Yan; Anthony E Kline; Amy K Wagner; James Lyons-Weiler; C Edward Dixon Journal: J Neurotrauma Date: 2013-02-05 Impact factor: 5.269
Authors: Ryan M McAdams; Bobbi Fleiss; Christopher Traudt; Leslie Schwendimann; Jessica M Snyder; Robin L Haynes; Niranjana Natarajan; Pierre Gressens; Sandra E Juul Journal: Dev Neurosci Date: 2017-05-10 Impact factor: 2.984