Literature DB >> 856983

Flavonoid constituents from Eupatorium altissimum L. (Compositae).

R H Dobberstein, M Tin-wa, H H Fong, F A Crane, N R Farnsworth.   

Abstract

An aqueous ethanol extract of Eupatorium altissimum L. (Compositae) showed confirmed activity in the P-388 lymphocytic leukemia assay in mice, and the chloroform solubles showed both cytotoxic activity in the 9KB carcinoma of the nasopharynx cell culture assay and antitumor activity in the P-388 lymphocytic leukemia assay. Two flavones, eupatorin and 5-hydroxy-3',4',6,7-tetramethoxyflavone, were isolated and identified. Both were devoid of cytotoxic and antitumor activity.

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Year:  1977        PMID: 856983     DOI: 10.1002/jps.2600660441

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

Review 1.  Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives.

Authors:  H Hendriks; T M Malingré; E T Elema
Journal:  Pharm Weekbl Sci       Date:  1983-12-16
  1 in total

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