Literature DB >> 8566941

Programs, databases, and expert systems for human geneticists--a survey.

C Fischer1, S Schweigert, C Spreckelsen, F Vogel.   

Abstract

We present an overview of the variety of databases and programs that offer substantial aid to medical and molecular geneticists. Databases and expert systems for genetic diseases and birth defects, programs for segregation and linkage analysis, certain DNA and protein sequence databases, and information resources in general for molecular biology are addressed. These systems cannot be used effectively without the newly developed techniques of information exchange based on international computer networks. A short introduction is given to the Internet and to European institutions and organizations that offer help with the acquisition and use of bioinformatic resources.

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Year:  1996        PMID: 8566941     DOI: 10.1007/bf02265253

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  57 in total

1.  The National Center for Biotechnology Information.

Authors:  D Benson; M Boguski; D Lipman; J Ostell
Journal:  Genomics       Date:  1990-02       Impact factor: 5.736

2.  A new estimate of the linkage between the genes for colourblindness and haemophilia in man.

Authors:  J B S HALDANE; C A B SMITH
Journal:  Ann Eugen       Date:  1947-10

3.  A visual interface to computer programs for linkage analysis.

Authors:  C J Chapman
Journal:  Am J Med Genet       Date:  1990-06

4.  Segregation analysis of quantitative traits in nuclear families: comparison of three program packages.

Authors:  L W Konigsberg; C M Kammerer; J W MacCluer
Journal:  Genet Epidemiol       Date:  1989       Impact factor: 2.135

5.  A new method to test genetic models in HLA associated diseases: the MASC method.

Authors:  F Clerget-Darpoux; M C Babron; B Prum; G M Lathrop; I Deschamps; J Hors
Journal:  Ann Hum Genet       Date:  1988-07       Impact factor: 1.670

6.  Applications of the MEGADATS database system in medical genetics.

Authors:  E A Yount; P M Conneally; J M Gersting
Journal:  Am J Med Genet       Date:  1987-10

7.  Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1974-09       Impact factor: 11.025

8.  Genealogy data design appropriate for family relationship retrieving.

Authors:  J Kern; S Vuletić
Journal:  Med Inform (Lond)       Date:  1993 Jan-Mar

9.  LABMAN and LINKMAN: a data management system specifically designed for genome searches of complex diseases.

Authors:  P Adams
Journal:  Genet Epidemiol       Date:  1994       Impact factor: 2.135

10.  Computerized approach to X-linked mental retardation syndromes.

Authors:  J F Arena; H A Lubs
Journal:  Am J Med Genet       Date:  1991 Feb-Mar
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  3 in total

1.  Computer support for genetic advice in primary care.

Authors:  J Emery
Journal:  Br J Gen Pract       Date:  1999-07       Impact factor: 5.386

Review 2.  Advances in genetics.

Authors:  M M Lees; R M Winter
Journal:  Arch Dis Child       Date:  1996-10       Impact factor: 3.791

3.  Computer support for recording and interpreting family histories of breast and ovarian cancer in primary care (RAGs): qualitative evaluation with simulated patients.

Authors:  J Emery; R Walton; A Coulson; D Glasspool; S Ziebland; J Fox
Journal:  BMJ       Date:  1999-07-03
  3 in total

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