Literature DB >> 8566760

Analysis of Staphylococcus aureus genes encoding penicillin-binding protein 4 and an ABC-type transporter.

T L Domanski1, K W Bayles.   

Abstract

A region of the Staphylococcus aureus chromosome has been isolated that contains the gene encoding penicillin-binding protein 4 (PBP4), as well as abcA, a gene that encodes a protein with strong sequence similarity to the ABC transporter family of proteins. A disruption in abcA by Campbell-type integration results in cells that display an increased resistance to methicillin and cefoxitin, two antibiotics known to interact with low-molecular-weight PBPs. Based on these observations, a potential regulatory link between these two genes is discussed.

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Year:  1995        PMID： 8566760     DOI： 10.1016/0378-1119(96)82965-9

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  13 in total

1.  The AbcA transporter of Staphylococcus aureus affects cell autolysis.

Authors:  G Schrader-Fischer; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  2001-02       Impact factor: 5.191

2.  Novel non-mecA-containing staphylococcal chromosomal cassette composite island containing pbp4 and tagF genes in a commensal staphylococcal species: a possible reservoir for antibiotic resistance islands in Staphylococcus aureus.

Authors:  Kanokporn Mongkolrattanothai; Susan Boyle; Trudy V Murphy; Robert S Daum
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

Review 3.  Bacterial cell wall synthesis: new insights from localization studies.

Authors:  Dirk-Jan Scheffers; Mariana G Pinho
Journal:  Microbiol Mol Biol Rev       Date:  2005-12       Impact factor: 11.056

4.  The transcriptional regulators NorG and MgrA modulate resistance to both quinolones and beta-lactams in Staphylococcus aureus.

Authors:  Que Chi Truong-Bolduc; David C Hooper
Journal:  J Bacteriol       Date:  2007-02-02       Impact factor: 3.490

5.  Present and future problems of antibiotic resistance in gram-positive cocci.

Authors:  J Jeljaszewicz; G Młynarczyk; A Młynarczyk
Journal:  Infection       Date:  1998 Jan-Feb       Impact factor: 3.553

6.  Penicillin-binding protein 4 overproduction increases beta-lactam resistance in Staphylococcus aureus.

Authors:  U U Henze; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  1996-09       Impact factor: 5.191

7.  Transcription analysis of the Staphylococcus aureus gene encoding penicillin-binding protein 4.

Authors:  T L Domanski; B L de Jonge; K W Bayles
Journal:  J Bacteriol       Date:  1997-04       Impact factor: 3.490

8.  Cloning, characterization, and inactivation of the gene pbpC, encoding penicillin-binding protein 3 of Staphylococcus aureus.

Authors:  M G Pinho; H de Lencastre; A Tomasz
Journal:  J Bacteriol       Date:  2000-02       Impact factor: 3.490

9.  Regulation of expression of abcA and its response to environmental conditions.

Authors:  Regis A Villet; Que Chi Truong-Bolduc; Yin Wang; Zoe Estabrooks; Heidi Medeiros; David C Hooper
Journal:  J Bacteriol       Date:  2014-02-07       Impact factor: 3.490

10.  A mutation in the D,D-carboxypeptidase penicillin-binding protein 3 of Streptococcus pneumoniae contributes to cefotaxime resistance of the laboratory mutant C604.

Authors:  J Krauss; R Hakenbeck
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191
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