| Literature DB >> 8564928 |
M García-Rocha1, P Bonay, J Avila.
Abstract
The target for the antitumoral peptidic drug, Kahalalide F, has been studied in cultured cells. In the presence of the compound, the cells became impressively swollen, showing the formation of large vacuoles. The formation of these vacuoles appears to be the consequence of changes in lysosomal membranes. Thus, lysosomes are a target for Kahalalide F action.Entities:
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Year: 1996 PMID： 8564928 DOI： 10.1016/0304-3835(95)04036-6
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679