| Literature DB >> 856486 |
J C Liao, N E Hoffman, J J Barboriak, D A Roth.
Abstract
Pyruvic and alpha-ketoglutaric acids were quantitatively and rapidly converted to quinoxalones by a new method, to enhance their detectability in the ultraviolet. The quinoxalones were separated by reversed-phase chromatography with use of 10 micronm particles packed in a 30-cm (length) column. An aqueous solution of ammonium acetate and methanol was used for linear gradient elution. The urinary excretion of pyruvic and alpha-ketoglutaric acids by normal individuals, diabetic patients, and patients with renal dysfunction was determined.Entities:
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Year: 1977 PMID： 856486
Source DB: PubMed Journal: Clin Chem ISSN： 0009-9147 Impact factor: 8.327