| Literature DB >> 8564411 |
M Gordaliza1, J M del Corral, M A Castro, M L López-Vázquez, A San Feliciano, M D García-Grávalos, A Carpy.
Abstract
A series of fused pyrazole derivatives of cyclolignans have been prepared through simple chemical routes and evaluated for their cytotoxic activities in culture cells of P-388 murine leukemia, A-549 lung carcinoma and HT-29 colon carcinoma. Despite the lack of the lactone moiety in their structures, they show IC50 values at microM levels.Entities:
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Year: 1995 PMID： 8564411 DOI： 10.1016/0968-0896(95)00091-t
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641