Literature DB >> 8564360

Prospects for new vaccines against tuberculosis.

I M Orme1.   

Abstract

The spectacular failure of the existing bacille Calmette-Guérin (BCG) vaccine in recent tuberculosis-control trials has prompted a search for potential replacements. Imaginative approaches currently under development include the modulation of BCG by the production of auxotrophic mutants or cytokine-secreting recombinants, and the development of subunit vaccines based on the major proteins of Mycobacterium tuberculosis.

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Year:  1995        PMID： 8564360     DOI： 10.1016/s0966-842x(00)88987-8

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  19 in total

1.  West African donors have high percentages of activated cytokine producing T cells that are prone to apoptosis.

Authors:  K Kemp; B D Akanmori; L Hviid
Journal:  Clin Exp Immunol       Date:  2001-10       Impact factor: 4.330

Review 2.  BCG and tuberculosis.

Authors:  M J Bannon
Journal:  Arch Dis Child       Date:  1999-01       Impact factor: 3.791

3.  Elements of signal transduction in Mycobacterium tuberculosis: in vitro phosphorylation and in vivo expression of the response regulator MtrA.

Authors:  L E Via; R Curcic; M H Mudd; S Dhandayuthapani; R J Ulmer; V Deretic
Journal:  J Bacteriol       Date:  1996-06       Impact factor: 3.490

4.  Role of RpoS in fine-tuning the synthesis of Vi capsular polysaccharide in Salmonella enterica serotype Typhi.

Authors:  Javier Santander; Soo-Young Wanda; Cheryl A Nickerson; Roy Curtiss
Journal:  Infect Immun       Date:  2006-12-18       Impact factor: 3.441

5.  Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis.

Authors:  S L Baldwin; C D'Souza; A D Roberts; B P Kelly; A A Frank; M A Lui; J B Ulmer; K Huygen; D M McMurray; I M Orme
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

6.  Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis.

Authors:  Smriti Mehra; Xavier Alvarez; Peter J Didier; Lara A Doyle; James L Blanchard; Andrew A Lackner; Deepak Kaushal
Journal:  J Infect Dis       Date:  2012-12-18       Impact factor: 5.226

7.  CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge.

Authors:  S Gurunathan; K R Irvine; C Y Wu; J I Cohen; E Thomas; C Prussin; N P Restifo; R A Seder
Journal:  J Immunol       Date:  1998-11-01       Impact factor: 5.422

8.  Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.

Authors:  Smriti Mehra; Bapi Pahar; Noton K Dutta; Cecily N Conerly; Kathrine Philippi-Falkenstein; Xavier Alvarez; Deepak Kaushal
Journal:  PLoS One       Date:  2010-08-31       Impact factor: 3.240

9.  Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis.

Authors:  M Gonzalez-Juarrero; I M Orme
Journal:  Infect Immun       Date:  2001-02       Impact factor: 3.441

10.  Animal models of mycobacteria infection.

Authors:  I M Orme; A D Roberts
Journal:  Curr Protoc Immunol       Date:  2001-05
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