Literature DB >> 856290

Distribution of prostaglandin biosynthetic pathways in several rat tissues. Formation of 6-ketoprostaglandin F1alpha.

C R Pace-Asciak, G Rangaraj.   

Abstract

The capacity of homogenates of rat lung, liver, spleen, whole stomach, stomach fundus, kidney and heart to form prostaglandin E2, F2alpha, D2, thromboxane B2 and 6-ketoprostaglandin F1alpha was investigated. All products were quantitated by mass spectrometry. The results demonstrated interesting differences between tissues in the direction of the 'prostaglandin synthetase' to specific products (e.g. as in spleen and stomach).

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Year:  1977        PMID: 856290     DOI: 10.1016/0005-2760(77)90112-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  18 in total

1.  Lungs as a generator of prostacyclin--hypothesis on physiological significance.

Authors:  R J Gryglewski; R Korbut; A Ocetkiewicz; J Spławiński; B Wojtaszek; J Swies
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-08       Impact factor: 3.000

2.  Prostaglandin excretion in Bartter's syndrome.

Authors:  H G Güllner
Journal:  Klin Wochenschr       Date:  1983-01-03

3.  Stimulation and inhibition of prostacyclin formation in the gastric mucosa and ileum in vitro by anti-inflammatory agents.

Authors:  N K Boughton-Smith; B J Whittle
Journal:  Br J Pharmacol       Date:  1983-01       Impact factor: 8.739

4.  Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid.

Authors:  E Vicenzi; A Biondi; C Bordignon; A Rambaldi; M B Donati; A Mantovani
Journal:  Clin Exp Immunol       Date:  1984-08       Impact factor: 4.330

5.  Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production.

Authors:  K D Rainsford; C Willis
Journal:  Dig Dis Sci       Date:  1982-07       Impact factor: 3.199

6.  Prostaglandin formation from exogenous precursor in homogenates of human cardiac tissue.

Authors:  R Brandt; J Nowak; T Sonnenfeld
Journal:  Basic Res Cardiol       Date:  1984 Mar-Apr       Impact factor: 17.165

7.  Kidney lipids: changes caused by dietary 9-trans, 12-trans-octadecadienoate.

Authors:  J E Kinsella; P H Yu; J B Mai
Journal:  Lipids       Date:  1979-12       Impact factor: 1.880

8.  Prostaglandin-H synthase mediated metabolism and mutagenic activation of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ).

Authors:  E Wolz; D Wild; G H Degen
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

9.  Dissociation between the effects of zymosan on the systemic and pulmonary vessels of the rat.

Authors:  J Damas; D Lagneaux
Journal:  Br J Pharmacol       Date:  1991-10       Impact factor: 8.739

10.  Protective effects of prostaglandins against ulcerogenic activity of indomethacin during different stages of erosion development in rat stomach. Role of acid and bicarbonate secretion.

Authors:  A A van Kolfschoten; F Hagelen; F C Hillen; L P Jager; P Zandberg; J van Noordwijk
Journal:  Dig Dis Sci       Date:  1983-12       Impact factor: 3.199

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