Literature DB >> 8562398

Cytomegalovirus-induced thrombocytopenia and haemolysis in an immunocompetent adult.

D J van Spronsen1, W P Breed.   

Abstract

We describe a patient with severe symptomatic thrombocytopenia and haemolytic anaemia caused by cytomegalovirus (CMV) infection. As far as we know, this is the second case in the literature. Treatment with ganciclovir seemed to be more effective for thrombocytopenia than treatment with corticosteroids. The hypothetical mechanisms leading to thrombocytopenia and haemolysis in CMV infection are briefly discussed. In cases of acute thrombocytopenia and clinical manifestations of an infectious disease, with or without haemolysis, testing for CMV may be useful in connection with therapeutic consequences.

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Year:  1996        PMID: 8562398     DOI: 10.1046/j.1365-2141.1996.00288.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  5 in total

1.  Cytomegalovirus reactivation exacerbated thrombocytopenia and haemolysis in a patient with systemic lupus erythematosus.

Authors:  Toshiro Sugimoto; Masahiro Aoyama; Naoko Takeda; Masayoshi Sakaguchi; Yoshihiko Nishio; Takashi Uzu; Atsunori Kashiwagi
Journal:  Rheumatol Int       Date:  2007-06-13       Impact factor: 2.631

2.  Hemolytic anemia due to acute cytomegalovirus infection in an immunocompetent adult: a case report and review of the literature.

Authors:  Fabrizio Taglietti; Cecilia M Drapeau; Elisabetta Grilli; Alessandro Capone; Pasquale Noto; Simone Topino; Nicola Petrosillo
Journal:  J Med Case Rep       Date:  2010-10-21

3.  Coombs-negative severe haemolytic anaemia in an immunocompetent adult following cytomegalovirus infection.

Authors:  W Veldhuis; M Janssen; W Kortlandt; A van Houte; M van de Ree
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2004-10-20       Impact factor: 3.267

4.  Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis.

Authors:  Raymond S M Wong; Alan Wu; K F To; Nelson Lee; Christopher W K Lam; C K Wong; Paul K S Chan; Margaret H L Ng; L M Yu; David S Hui; John S Tam; Gregory Cheng; Joseph J Y Sung
Journal:  BMJ       Date:  2003-06-21

5.  Refractory Immune Thrombocytopenic Purpura and Cytomegalovirus Infection: A Call for a Change in the Current Guidelines.

Authors:  Alexei Shimanovsky; Devbala Patel; Jeffrey Wasser
Journal:  Mediterr J Hematol Infect Dis       Date:  2016-01-01       Impact factor: 2.576

  5 in total

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