OBJECTIVE: To assess the likely impact on HIV incidence of increased condom use, a reduction in casual sexual partners, treatment programmes for other sexually transmitted diseases (STD) and combinations of these in rural Uganda. METHODS: A simulation model for the transmission dynamics of HIV infection and STD was employed, drawing on data from a rural population cohort in South-West Uganda with an HIV prevalence of 9% among adults in 1990. RESULTS: For the scenario most consistent with data from the study population, 39% of all adult HIV infections were averted, in the 10 years from 1990, when condoms were used consistently and effectively by 50% of men in their contacts with one-off sexual partners (such as bar girls and commercial sex workers). Reducing by 50% the frequency of men's sexual contacts with one-off partners averted 68% of infections. Reducing by 50% the duration of all STD episodes averted 43% of infections. Combining these three interventions averted 82% of all adult infections in the 10 years from 1990. CONCLUSION: A substantial proportion of HIV infections may be averted in general populations through interventions targeted only on less regular sexual partnerships.
OBJECTIVE: To assess the likely impact on HIV incidence of increased condom use, a reduction in casual sexual partners, treatment programmes for other sexually transmitted diseases (STD) and combinations of these in rural Uganda. METHODS: A simulation model for the transmission dynamics of HIV infection and STD was employed, drawing on data from a rural population cohort in South-West Uganda with an HIV prevalence of 9% among adults in 1990. RESULTS: For the scenario most consistent with data from the study population, 39% of all adult HIV infections were averted, in the 10 years from 1990, when condoms were used consistently and effectively by 50% of men in their contacts with one-off sexual partners (such as bar girls and commercial sex workers). Reducing by 50% the frequency of men's sexual contacts with one-off partners averted 68% of infections. Reducing by 50% the duration of all STD episodes averted 43% of infections. Combining these three interventions averted 82% of all adult infections in the 10 years from 1990. CONCLUSION: A substantial proportion of HIV infections may be averted in general populations through interventions targeted only on less regular sexual partnerships.
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Keywords:
Acquired Immunodeficiency Syndrome--prevention and control; Africa; Africa South Of The Sahara; Barrier Methods; Behavior; Biology; Condom; Contraception; Contraceptive Methods; Demographic Factors; Developing Countries; Diseases; Eastern Africa; English Speaking Africa; Family Planning; Hiv Infections--prevention and control; Infections; Models, Theoretical; Population; Population Characteristics; Reproductive Tract Infections; Research Methodology; Risk Behavior; Risk Factors; Rural Population; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Uganda; Viral Diseases
Authors: Amy A Conroy; Stacey A McKenna; Megan L Comfort; Lynae A Darbes; Judy Y Tan; James Mkandawire Journal: Soc Sci Med Date: 2018-08-20 Impact factor: 4.634
Authors: Richard G Wamai; Brian J Morris; Stefan A Bailis; David Sokal; Jeffrey D Klausner; Ross Appleton; Nelson Sewankambo; David A Cooper; John Bongaarts; Guy de Bruyn; Alex D Wodak; Joya Banerjee Journal: J Int AIDS Soc Date: 2011-10-20 Impact factor: 5.396