Scanning electron microscope study of the extracellular matrix between presumptive lens and presumptive retina of the chick embryo.

The three-dimensional architecture of the intercellular matrix contained in the interspace between the presumptive lens and optic vesicle of the chick embryo was examined by scanning electron microsocpy. The fibrous structure of the basement membranes lining the space was demonstrated. The space was shown to be filled with a dense fibrous meshwork. The reaction of basement membranes and interspace contents to enzymic digestion is described. The functional significance of the arrangement of fibres in the interspace is discussed.