Literature DB >> 8559002

[Local recurrence of soft tissue sarcoma of the extremities and trunk].

M Peiper1, D Zurakowski, C Zornig.   

Abstract

Soft tissue sarcomas (STS) tend to recur locally. In a series of 140 patients operated on during the past two decades with STS of the extremities and trunk, prognostic factors influencing local recurrence were determined. Statistical significance was evaluated for the quality of surgical resection (P < 0.001), regional positive lymph nodes (P = 0.03), and adjuvant radiotherapy (P = 0.01) [for resection without wide margins (R1) and low-grade (G3) tumors]. In 1988, the surgical procedure was standardized. After 1987, local recurrence decreased significantly (P < 0.001). In subfascial tumors, local recurrence occurred far less in cases of compartmental resection than with wide excision. These data indicate that the course of patients with STS can be beneficially influenced by optimal therapy. Resection with wide margins in all three dimensions is the aim of sarcoma surgery. Postoperative radiation therapy is indicated in the case of R1 resection.

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Year:  1995        PMID: 8559002     DOI: 10.1007/bf00207221

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN: 0023-8236


  29 in total

1.  The effect of local recurrence on survival time in adult high-grade soft tissue sarcomas.

Authors:  L J Emrich; W Ruka; D L Driscoll; C P Karakousis
Journal:  J Clin Epidemiol       Date:  1989       Impact factor: 6.437

Review 2.  Combined surgery and radiation therapy for limb preservation in soft tissue sarcoma of the extremity: the Massachusetts General Hospital experience.

Authors:  I J Spiro; A E Rosenberg; D Springfield; H Suit
Journal:  Cancer Invest       Date:  1995       Impact factor: 2.176

3.  Adjuvant chemotherapy with doxorubicin in high-grade soft tissue sarcoma: a randomized trial of the Scandinavian Sarcoma Group.

Authors:  T A Alvegård; H Sigurdsson; H Mouridsen; O Solheim; B Unsgaard; U Ringborg; O Dahl; A M Nordentoft; C Blomqvist; A Rydholm
Journal:  J Clin Oncol       Date:  1989-10       Impact factor: 44.544

4.  Soft tissue sarcomas of the extremities and trunk in the adult. Report of 124 cases.

Authors:  C Zornig; H J Weh; A Krüll; R Schwarz; R E Hilgert; S Schröder
Journal:  Langenbecks Arch Chir       Date:  1992

5.  Staging of soft-tissue sarcomas. Prognostic analysis of clinical and pathological features.

Authors:  M K Saddegh; J Lindholm; A Lundberg; U Nilsonne; A Kreicbergs
Journal:  J Bone Joint Surg Br       Date:  1992-07

6.  Localized extremity soft tissue sarcoma: an analysis of factors affecting survival.

Authors:  C Collin; J Godbold; S Hajdu; M Brennan
Journal:  J Clin Oncol       Date:  1987-04       Impact factor: 44.544

7.  Surgery for soft tissue sarcoma in the extremities. A multivariate analysis of the 6-26-year prognosis in 137 patients.

Authors:  O Berlin; B Stener; L Angervall; L G Kindblom; G Markhede; A Odén
Journal:  Acta Orthop Scand       Date:  1990-12

8.  Primary reexcision for patients with 'microscopic residual' tumor following initial excision of sarcomas of trunk and extremity sites.

Authors:  D M Hays; W Lawrence; M Wharam; W Newton; F B Ruymann; M Beltangady; H M Maurer
Journal:  J Pediatr Surg       Date:  1989-01       Impact factor: 2.545

9.  [Tumors and tumor-like changes in soft tissues. Revision of the study population, histogenic classification and differential diagnosis].

Authors:  H P Meister; P H Wünsch; E A Konrad; T Kirchner
Journal:  Pathologe       Date:  1980-11       Impact factor: 1.011

10.  Preoperative radiation therapy for sarcoma of soft tissue.

Authors:  H D Suit; K H Proppe; H J Mankin; W C Wood
Journal:  Cancer       Date:  1981-05-01       Impact factor: 6.860

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  3 in total

1.  Compartmental resection for subfascial extremity soft tissue sarcoma and quality of life in long-term survivors.

Authors:  Matthias Peiper; Hanno Matthaei; Edwin Bölke; David Zurakowski; Klaus Orth; Antje Heinecke; Wolfram Trudo Knoefel
Journal:  Wien Klin Wochenschr       Date:  2011-07-12       Impact factor: 1.704

2.  Superficial soft tissue sarcomas of the extremities and trunk.

Authors:  Anja Lachenmayer; Qin Yang; Claus F Eisenberger; Edwin Boelke; Christopher Poremba; Antje Heinecke; Christian Ohmann; Wolfram Trudo Knoefel; Matthias Peiper
Journal:  World J Surg       Date:  2009-08       Impact factor: 3.352

3.  Treatment of resectable intrathoracic sarcomas: a single institution experience over twenty years.

Authors:  David Rainey; Jacob Berriochoa; Anna Korpak; Jing Zeng; Elizabeth T Loggers; Robin L Jones; Shilpen Patel
Journal:  J Radiat Oncol       Date:  2015-12-16
  3 in total

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