Literature DB >> 8557595

Bassiatin, a new platelet aggregation inhibitor produced by Beauveria bassiana K-717.

T Kagamizono1, E Nishino, K Matsumoto, A Kawashima, M Kishimoto, N Sakai, B M He, Z X Chen, T Adachi, S Morimoto.   

Abstract

A new platelet aggregation inhibitor, bassiatin, was isolated from the cultured broth of Beauveria bassiana which had been isolated from a soil sample collected in Yunnan province, China. The structure of bassiatin was determined to be (3S, 6R)-4-methyl-6-(1-methylethyl)-3-phenylmethyl-1, 4-perhydrooxazine-2,5-dione by NMR analysis, X-ray crystallographic analysis and chemical synthesis. Bassiatin inhibited ADP-induced aggregation of rabbit platelets with the IC50 being 1.9 x 10(-4) M.

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Year:  1995        PMID： 8557595     DOI： 10.7164/antibiotics.48.1407

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

1.  Discovery of secondary metabolites in an extractive liquid-surface immobilization system and its application to high-throughput interfacial screening of antibiotic-producing fungi.

Authors:  Shinobu Oda; Arisa Kameda; Masanori Okanan; Yusuke Sakakibara; Shinichi Ohashi
Journal:  J Antibiot (Tokyo)       Date:  2015-05-13       Impact factor: 2.649

2.  Shornephine A: structure, chemical stability, and P-glycoprotein inhibitory properties of a rare diketomorpholine from an Australian marine-derived Aspergillus sp.

Authors:  Zeinab G Khalil; Xiao-cong Huang; Ritesh Raju; Andrew M Piggott; Robert J Capon
Journal:  J Org Chem       Date:  2014-09-02       Impact factor: 4.354

3.  Isolation, purification and identification of biological compounds from Beauveria sp. and their evaluation as insecticidal effectiveness against Bemisia tabaci.

Authors:  Ran An; Maqsood Ahmed; Haiyan Li; Yanbin Wang; Aimin Zhang; Yuhui Bi; Zhiguo Yu
Journal:  Sci Rep       Date:  2021-06-08       Impact factor: 4.379

Review 4.  Genome Studies on Nematophagous and Entomogenous Fungi in China.

Authors:  Weiwei Zhang; Xiaoli Cheng; Xingzhong Liu; Meichun Xiang
Journal:  J Fungi (Basel)       Date:  2016-02-05

5.  Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces sp. L-8 and Their Cytotoxic Activity.

Authors:  Li-Hong Huang; Yan-Xiu Chen; Jian-Chen Yu; Jie Yuan; Hou-Jin Li; Wen-Zhe Ma; Ramida Watanapokasin; Kun-Chao Hu; Shah Iram Niaz; De-Po Yang; Wen-Jian Lan
Journal:  Molecules       Date:  2017-03-11       Impact factor: 4.411

6.  Genomic and Experimental Analysis of the Insecticidal Factors Secreted by the Entomopathogenic Fungus Beauveria pseudobassiana RGM 2184.

Authors:  Fabiola Altimira; Matias Arias-Aravena; Ling Jian; Nicolas Real; Pablo Correa; Carolina González; Sebastián Godoy; Jean Franco Castro; Olga Zamora; Cristina Vergara; Nancy Vitta; Eduardo Tapia
Journal:  J Fungi (Basel)       Date:  2022-03-01
  6 in total

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