Literature DB >> 855714

Xanthine oxidase activity in a gouty patient with partial deficiency of HGPRT.

A Carcassi.   

Abstract

A patient with juvenile gout and partial deficiency of HGPRT is presented. In this subject, hepatic xanthine oxidase activity showed a twelve-fold increase. Xanthine oxidase is a readily induced enzyme and this increased activity is probably correlated with the increased availability of hypoxanthine observed in such patients.

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Year:  1977        PMID: 855714     DOI: 10.1007/978-1-4613-4223-6_43

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

1.  Overproduction of uric acid in hypoxanthine-guanine phosphoribosyltransferase deficiency. Contribution by impaired purine salvage.

Authors:  N L Edwards; D Recker; I H Fox
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

  1 in total

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