Literature DB >> 8555769

[Comparison between various methods of pregnancy screening during a large-scale ivermectin treatment in Cameroon].

J P Chippaux1, N Gardon-Wendel, J C Ernould, J Gardon.   

Abstract

During a mass treatment with ivermectin which is contraindicated to pregnant women, authors made a screening for pregnancy by questioning 2,580 women from 15 to 45 years old. 1,409 of these women were also interrogated by a female physician assisted by a native matron to detect pregnant women. In 1,798 women, at least one immunological pregnancy test has been used in the field. A nine months follow-up was made to check answers. Women's knowledge led to a good appreciation of pregnancy as they correctly appreciated their pregnancy from the second month: specificity was good (98%) but sensitivity was moderate (71%). Conclusions made by gynecological team after detailed questionnaire were more sensitive (80%), but specificity decrease dramatically to 59%. Combinations of several items in the questionnaire showed no benefit. Sensitivity of the various immunological pregnancy tests tried was included in 70 to 90% and specificity was varying from 87 to 97%. Simple questioning of women was the most efficient method (efficiency value was 94% against 63% for interview and 92% for pregnancy tests). However, the use of this method induced the risk that about 29% of women have been treated although they were pregnant.

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Year:  1995        PMID: 8555769

Source DB:  PubMed          Journal:  Bull Soc Pathol Exot        ISSN: 0037-9085


  3 in total

1.  Ruling out early trimester pregnancy when implementing community-based deworming programs.

Authors:  Kariane St-Denis; Brittany Blouin; Elham Rahme; Martin Casapia; Antonio Montresor; Denise Mupfasoni; Pamela Sabina Mbabazi; Theresa W Gyorkos
Journal:  PLoS Negl Trop Dis       Date:  2020-01-30

2.  Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis.

Authors:  Patricia Nicolas; Marta F Maia; Quique Bassat; Kevin C Kobylinski; Wuelton Monteiro; N Regina Rabinovich; Clara Menéndez; Azucena Bardají; Carlos Chaccour
Journal:  Lancet Glob Health       Date:  2020-01       Impact factor: 38.927

3.  Treatment of Pregnant Women with Ivermectin during Mass Drug Distribution: Time to Investigate Its Safety and Potential Benefits.

Authors:  Astrid Christine Erber; Esther Ariyo; Piero Olliaro; Patricia Nicolas; Carlos Chaccour; Robert Colebunders
Journal:  Pathogens       Date:  2021-12-08
  3 in total

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