Literature DB >> 8554623

Chlorogenic acid as a natural scavenger for hypochlorous acid.

Y Kono1, H Shibata, Y Kodama, A Ueda, Y Sawa.   

Abstract

The effect of chlorogenic acid (CGA) on the killing of Escherichia coli by hypochlorous acid (HOCI) was examined. CGA prevented E. coli from bactericidal action of HOCI in a concentration-dependent manner. HOCI reacted rapidly with CGA. By comparison with the one- and two-electron oxidation products produced by peroxidase and phenolase reactions, respectively, the main product was identified as o-quinone of CGA via the formation of o-semiquinone of CGA as an intermediate The quinone form of CGA reacted further with HOCI to yield unstable product(s).

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Year:  1995        PMID: 8554623     DOI: 10.1006/bbrc.1995.2865

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  4 in total

1.  Effectiveness of phenoxyl radicals generated by peroxidase/H2O2-catalyzed oxidation of caffeate, ferulate, and p-coumarate in cooxidation of ascorbate and NADH.

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Journal:  J Plant Res       Date:  2007-12-11       Impact factor: 2.629

Review 2.  Myeloperoxidase: a target for new drug development?

Authors:  E Malle; P G Furtmüller; W Sattler; C Obinger
Journal:  Br J Pharmacol       Date:  2007-06-25       Impact factor: 8.739

3.  Comparative pharmacokinetics of chlorogenic acid in beagles after oral administrations of single compound, the extracts of Lonicera japanica, and the mixture of chlorogenic acid, baicalin, and Forsythia suspense.

Authors:  Rong Liu; Ke Lai; Yu Xiao; Jing Ren
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

4.  Increased ROS Scavenging and Antioxidant Efficiency of Chlorogenic Acid Compound Delivered via a Chitosan Nanoparticulate System for Efficient In Vitro Visualization and Accumulation in Human Renal Adenocarcinoma Cells.

Authors:  Revathi Kavi Rajan; Mohd Zobir Hussein; Sharida Fakurazi; Khatijah Yusoff; Mas Jaffri Masarudin
Journal:  Int J Mol Sci       Date:  2019-09-20       Impact factor: 5.923

  4 in total

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