Literature DB >> 8553310

Recombinant human DNase in management of lobar atelectasis due to retained secretions.

B A Touleimat1, C S Conoscenti, J M Fine.   

Abstract

Recombinant human deoxyribonuclease (rhDNase) is an agent which reduces the viscoelasticity of purulent sputum. Two cases are reported in which rhDNase was utilised for the management of lobar atelectasis due to retained purulent secretions.

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Year:  1995        PMID： 8553310      PMCID： PMC1021360          DOI： 10.1136/thx.50.12.1319

Source DB:  PubMed          Journal:  Thorax        ISSN： 0040-6376            Impact factor:   9.139


  8 in total

1.  A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.

Authors:  R C Hubbard; N G McElvaney; P Birrer; S Shak; W W Robinson; C Jolley; M Wu; M S Chernick; R G Crystal
Journal:  N Engl J Med       Date:  1992-03-19       Impact factor: 91.245

2.  Liquefaction of viscous purulent exudates by deoxyribonuclease.

Authors:  J B ARMSTRONG; J C WHITE
Journal:  Lancet       Date:  1950-12-09       Impact factor: 79.321

3.  Acute lobar atelectasis: a prospective comparison of fiberoptic bronchoscopy and respiratory therapy.

Authors:  J J Marini; D J Pierson; L D Hudson
Journal:  Am Rev Respir Dis       Date:  1979-06

4.  Studies on pulmonary secretions. 3. The nucleic acids in whole pulmonary secretions from patients with cystic fibrosis, bronchiectasis, and laryngectomy.

Authors:  J L Potter; S Spector; L W Matthews; J Lemm
Journal:  Am Rev Respir Dis       Date:  1969-06

5.  Effects of periodic positive airway pressure by mask on postoperative pulmonary function.

Authors:  S E Ricksten; A Bengtsson; C Soderberg; M Thorden; H Kvist
Journal:  Chest       Date:  1986-06       Impact factor: 9.410

6.  Lobar atelectasis in cystic fibrosis and treatment with recombinant human DNase I.

Authors:  P L Shah; S F Scott; M E Hodson
Journal:  Respir Med       Date:  1994-04       Impact factor: 3.415

7.  Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.

Authors:  S Shak; D J Capon; R Hellmiss; S A Marsters; C L Baker
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

8.  Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group.

Authors:  H J Fuchs; D S Borowitz; D H Christiansen; E M Morris; M L Nash; B W Ramsey; B J Rosenstein; A L Smith; M E Wohl
Journal:  N Engl J Med       Date:  1994-09-08       Impact factor: 91.245
  8 in total
  1 in total

1.  Recombinant human deoxyribonuclease improves atelectasis in mechanically ventilated children with cardiac disease.

Authors:  Parthak Prodhan; B Greenberg; Adnan T Bhutta; Carrie Hyde; Ajay Vankatesan; Michiaki Imamura; Robert Db Jaquiss; Umesh Dyamenahalli
Journal:  Congenit Heart Dis       Date:  2009 May-Jun       Impact factor: 2.007
  1 in total

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