BACKGROUND: Stereotactic biopsy followed by cytoreductive surgery and/or radiation are the standard treatment for pineoblastoma. We are reporting a patient with a relatively large pineoblastoma, who was treated with a combination of nonresective treatment modalities. METHOD: The patient is a 20-year-old woman who presented with signs and symptoms of raised intracranial pressure. Magnetic resonance imaging (MRI) showed a large tumor in the pineal region and hydrocephalus. She was emergently treated by placement of a ventriculoperitoneal shunt. Three days later she underwent a stereotactic biopsy, which showed the tumor to be pineoblastoma. She was then further treated with the following treatment modalities: permanent implantation of high activity I125 seeds, external radiation, and chemotherapy. RESULTS: At 10 months' follow-up, MRI showed complete disappearance of the tumor. At 18 months' follow-up, the patient is asymptomatic, neurologically intact, and her MRI scans show no evidence of intracranial or intraspinal tumor. CONCLUSIONS: Though the follow-up is relatively short, the results of the nonresective approach in this patient have been excellent.
BACKGROUND: Stereotactic biopsy followed by cytoreductive surgery and/or radiation are the standard treatment for pineoblastoma. We are reporting a patient with a relatively large pineoblastoma, who was treated with a combination of nonresective treatment modalities. METHOD: The patient is a 20-year-old woman who presented with signs and symptoms of raised intracranial pressure. Magnetic resonance imaging (MRI) showed a large tumor in the pineal region and hydrocephalus. She was emergently treated by placement of a ventriculoperitoneal shunt. Three days later she underwent a stereotactic biopsy, which showed the tumor to be pineoblastoma. She was then further treated with the following treatment modalities: permanent implantation of high activity I125 seeds, external radiation, and chemotherapy. RESULTS: At 10 months' follow-up, MRI showed complete disappearance of the tumor. At 18 months' follow-up, the patient is asymptomatic, neurologically intact, and her MRI scans show no evidence of intracranial or intraspinal tumor. CONCLUSIONS: Though the follow-up is relatively short, the results of the nonresective approach in this patient have been excellent.
Authors: Mohammad Maarouf; Faycal El Majdoub; Christian Bührle; Jürgen Voges; Ralph Lehrke; Martin Kocher; Stefan Hunsche; Harald Treuer; Volker Sturm Journal: Strahlenther Onkol Date: 2010-02-22 Impact factor: 3.621
Authors: Senthil K Selvanathan; Oliver Richards; Saira Alli; Martin Elliott; Atul K Tyagi; Paul D Chumas Journal: Acta Neurochir (Wien) Date: 2019-05-18 Impact factor: 2.216
Authors: Christian Senft; Andreas Raabe; Elke Hattingen; Daniel Sommerlad; Volker Seifert; Kea Franz Journal: Neurosurg Rev Date: 2008-02-12 Impact factor: 3.042
Authors: S V Roopesh Kumar; Aaron Mohanty; Vani Santosh; Satyanarayana Satish; B Indira Devi; Shanti Shankar Praharaj; Sastry V R Kolluri Journal: Childs Nerv Syst Date: 2007-05-31 Impact factor: 1.475