Literature DB >> 8551826

Natural history of untreated cytomegalovirus retinitis.

E F Bowen1, P Wilson, M Atkins, S Madge, P D Griffiths, M A Johnson, V C Emery.   

Abstract

Cytomegalovirus infection is common in patients with AIDS, and often causes retinitis. Treatment is rarely curative, but the progression of retinitis is delayed. The untreated course of cytomegalovirus retinitis in AIDS is unknown. We report a 35-year-old man with retinitis who refused treatment. Retinitis resulted in blindness within 6 months. Measurement of cytomegalovirus genomes showed an increasing viral load in blood and urine.

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Year:  1995        PMID： 8551826     DOI： 10.1016/s0140-6736(95)92842-1

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  7 in total

Review 1.  Is cytomegalovirus viraemia a useful tool in managing CMV disease?

Authors:  J R Deayton
Journal:  Sex Transm Infect       Date:  2000-10       Impact factor: 3.519

2.  Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS.

Authors:  H H Balfour; C V Fletcher; A Erice; W K Henry; E P Acosta; S A Smith; M A Holm; G Boivin; D H Shepp; C S Crumpacker; C A Eaton; S S Martin-Munley
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

3.  Valganciclovir in the treatment of cytomegalovirus retinitis in HIV-infected patients.

Authors:  A Jayaprakash Patil; Ashish Sharma; M Cristina Kenney; Baruch D Kuppermann
Journal:  Clin Ophthalmol       Date:  2010-03-04

4.  The cytoplasmic tail of glycoprotein M (gpUL100) expresses trafficking signals required for human cytomegalovirus assembly and replication.

Authors:  Magdalena Krzyzaniak; Michael Mach; William J Britt
Journal:  J Virol       Date:  2007-07-11       Impact factor: 5.103

5.  Immune recovery uveitis associated with highly active antiretroviral therapy in a patient with CMV retinitis and AIDS despite a low CD4+ T cell count: case report and a review of the literature.

Authors:  Mehmet Numan Alp; Nurcan Baykam; Gulcan Kural
Journal:  Int Ophthalmol       Date:  2009-02-07       Impact factor: 2.031

6.  Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic.

Authors:  David Heiden; Nathan Ford; David Wilson; William R Rodriguez; Todd Margolis; Bart Janssens; Martha Bedelu; Nini Tun; Eric Goemaere; Peter Saranchuk; Kalpana Sabapathy; Frank Smithuis; Emmanuel Luyirika; W Lawrence Drew
Journal:  PLoS Med       Date:  2007-12       Impact factor: 11.069

Review 7.  Pathogenesis of human cytomegalovirus in the immunocompromised host.

Authors:  Paul Griffiths; Matthew Reeves
Journal:  Nat Rev Microbiol       Date:  2021-06-24       Impact factor: 60.633
  7 in total

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