Literature DB >> 8551825

Transmission of Ebola virus (Zaire strain) to uninfected control monkeys in a biocontainment laboratory.

N Jaax1, P Jahrling, T Geisbert, J Geisbert, K Steele, K McKee, D Nagley, E Johnson, G Jaax, C Peters.   

Abstract

Secondary transmission of Ebola virus infection in humans is known to be caused by direct contact with infected patients or body fluids. We report transmission of Ebola virus (Zaire strain) to two of three control rhesus monkeys (Macaca mulatta) that did not have direct contact with experimentally inoculated monkeys held in the same room. The two control monkeys died from Ebola virus infections at 10 and 11 days after the last experimentally inoculated monkey had died. The most likely route of infection of the control monkeys was aerosol, oral or conjunctival exposure to virus-laden droplets secreted or excreted from the experimentally inoculated monkeys. These observations suggest approaches to the study of routes of transmission to and among humans.

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Year:  1995        PMID: 8551825     DOI: 10.1016/s0140-6736(95)92841-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  63 in total

1.  Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine.

Authors:  J Brian Kimble; Delphine C Malherbe; Michelle Meyer; Bronwyn M Gunn; Marcus M Karim; Philipp A Ilinykh; Mathieu Iampietro; Khaled S Mohamed; Surendra Negi; Pavlo Gilchuk; Kai Huang; Yuri I Wolf; Werner Braun; James E Crowe; Galit Alter; Alexander Bukreyev
Journal:  J Virol       Date:  2019-02-05       Impact factor: 5.103

2.  A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge.

Authors:  Waranyoo Phoolcharoen; John M Dye; Jacquelyn Kilbourne; Khanrat Piensook; William D Pratt; Charles J Arntzen; Qiang Chen; Hugh S Mason; Melissa M Herbst-Kralovetz
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-05       Impact factor: 11.205

Review 3.  Filovirus vaccines.

Authors:  Steven B Bradfute; John M Dye; Sina Bavari
Journal:  Hum Vaccin       Date:  2011-06-01

4.  2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings.

Authors:  Jane D Siegel; Emily Rhinehart; Marguerite Jackson; Linda Chiarello
Journal:  Am J Infect Control       Date:  2007-12       Impact factor: 2.918

5.  Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: clinical characterization and risk factors for severe disease.

Authors:  Reed F Johnson; Lori E Dodd; Srikanth Yellayi; Wenjuan Gu; Jennifer A Cann; Catherine Jett; John G Bernbaum; Dan R Ragland; Marisa St Claire; Russell Byrum; Jason Paragas; Joseph E Blaney; Peter B Jahrling
Journal:  Virology       Date:  2011-10-19       Impact factor: 3.616

Review 6.  Animal Models of Ebolavirus Infection.

Authors:  Marisa C St Claire; Dan R Ragland; Laura Bollinger; Peter B Jahrling
Journal:  Comp Med       Date:  2017-06-01       Impact factor: 0.982

Review 7.  Epidemiology and Management of the 2013-16 West African Ebola Outbreak.

Authors:  M L Boisen; J N Hartnett; A Goba; M A Vandi; D S Grant; J S Schieffelin; R F Garry; L M Branco
Journal:  Annu Rev Virol       Date:  2016-08-15       Impact factor: 10.431

8.  Replication-deficient ebolavirus as a vaccine candidate.

Authors:  Peter Halfmann; Hideki Ebihara; Andrea Marzi; Yasuko Hatta; Shinji Watanabe; M Suresh; Gabriele Neumann; Heinz Feldmann; Yoshihiro Kawaoka
Journal:  J Virol       Date:  2009-02-11       Impact factor: 5.103

9.  Ebola Virus Shedding and Transmission: Review of Current Evidence.

Authors:  Pauline Vetter; William A Fischer; Manuel Schibler; Michael Jacobs; Daniel G Bausch; Laurent Kaiser
Journal:  J Infect Dis       Date:  2016-07-20       Impact factor: 5.226

10.  Ebola virus-like particles protect from lethal Ebola virus infection.

Authors:  Kelly L Warfield; Catharine M Bosio; Brent C Welcher; Emily M Deal; Mansour Mohamadzadeh; Alan Schmaljohn; M Javad Aman; Sina Bavari
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205

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