Literature DB >> 8550296

Serum antibody responses in opisthorchiasis.

P S Akai1, S Pungpak, W Chaicumpa, V Kitikoon, Y Ruangkunaporn, D Bunnag, A D Befus.   

Abstract

We evaluated an enzyme-linked immunosorbent assay using crude parasite homogenates as a diagnostic test for Opisthorchis viverrini infection in humans. Serum antibody (Ab) responses to O. viverrini adult worm homogenate (AWH) and metacercaria homogenate (MH) were studied in 83 infected residents of an opisthorchiasis-endemic area in Thailand. Elevated levels of Ab persisted for over 1 year following curative treatment with praziquantel, and cross-reactivity to O. viverrini AWH and MH antigens was observed in sera from individuals with other parasitic infections. Serum Ab to crude AWH and MH are therefore unsuitable for immunodiagnosis since they may be non-specific and would not differentiate between ongoing and past infection.

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Year:  1995        PMID: 8550296     DOI: 10.1016/0020-7519(94)00212-7

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN: 0020-7519            Impact factor:   3.981


  8 in total

Review 1.  Opisthorchis viverrini: the carcinogenic human liver fluke.

Authors:  Natthawut Kaewpitoon; Soraya-J Kaewpitoon; Prasit Pengsaa; Banchob Sripa
Journal:  World J Gastroenterol       Date:  2008-02-07       Impact factor: 5.742

2.  Detection of salivary antibodies to crude antigens of Opisthorchis viverrini in opisthorchiasis and cholangiocarcinoma patients.

Authors:  Ponlatham Chaiyarit; Paiboon Sithithaworn; Chanitra Thuwajit; Puangrat Yongvanit
Journal:  Clin Oral Investig       Date:  2010-05-06       Impact factor: 3.573

3.  Immunodiagnosis of opisthorchiasis using parasite cathepsin F.

Authors:  Salma Teimoori; Yuji Arimatsu; Thewarach Laha; Sasithorn Kaewkes; Piya Sereerak; Sirikachorn Tangkawattana; Paul J Brindley; Banchob Sripa
Journal:  Parasitol Res       Date:  2015-09-07       Impact factor: 2.289

4.  Rapid assessment of Opisthorchis viverrini IgG antibody in serum: A potential diagnostic biomarker to predict risk of cholangiocarcinoma in regions endemic for opisthorchiasis.

Authors:  Rutchanee Rodpai; Vor Luvira; Lakkhana Sadaow; Wattana Sukeepaisarnjaroen; Amnat Kitkhuandee; Krisada Paonariang; Oranuch Sanpool; Wannaporn Ittiprasert; Victoria H Mann; Pewpan M Intapan; Paul J Brindley; Wanchai Maleewong
Journal:  Int J Infect Dis       Date:  2021-12-23       Impact factor: 12.074

5.  Serum IgG as a Marker for Opisthorchis viverrini-Associated Cholangiocarcinoma Correlated with HER2 Overexpression.

Authors:  Attapol Titapun; Anchalee Techasen; Prakasit Sa-Ngiamwibool; Paiboon Sithithaworn; Vor Luvira; Tharatip Srisuk; Apiwat Jareanrat; Hasaya Dokduang; Watcharin Loilome; Bandit Thinkhamrop; Narong Khuntikeo
Journal:  Int J Gen Med       Date:  2020-11-26

6.  Validation of an excretory/secretory antigen based-ELISA for the diagnosis of Opisthorchis felineus infection in humans from low trematode endemic areas.

Authors:  Maria Angeles Gómez-Morales; Alessandra Ludovisi; Marco Amati; Edoardo Pozio
Journal:  PLoS One       Date:  2013-05-09       Impact factor: 3.240

7.  Microproteinuria during Opisthorchis viverrini infection: a biomarker for advanced renal and hepatobiliary pathologies from chronic opisthorchiasis.

Authors:  Prasert Saichua; Paiboon Sithithaworn; Amar R Jariwala; David J Diemert; David J Deimert; Jiraporn Sithithaworn; Banchob Sripa; Thewarach Laha; Eimorn Mairiang; Chawalit Pairojkul; Maria Victoria Periago; Narong Khuntikeo; Jason Mulvenna; Jeffrey M Bethony
Journal:  PLoS Negl Trop Dis       Date:  2013-05-23

8.  Comparative assessment of immunochromatographic test kits using somatic antigens from adult Opisthorchis viverrini and IgG and IgG4 conjugates for serodiagnosis of human opisthorchiasis.

Authors:  Weeraya Phupiewkham; Lakkhana Sadaow; Oranuch Sanpool; Rutchanee Rodpai; Hiroshi Yamasaki; Wannaporn Ittiprasert; Victoria H Mann; Paul J Brindley; Wanchai Maleewong; Pewpan M Intapan
Journal:  Parasitol Res       Date:  2021-07-14       Impact factor: 2.383

  8 in total

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