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Literature DB >> 8549714

In vitro activity of commercially manufactured disinfectants against Pseudomonas aeruginosa.

Abstract

The in vitro activity of 17 commercially manufactured disinfectants routinely used in a large teaching hospital was tested against 128 strains of Pseudomonas aeruginosa isolated from hospitalized patients and the hospital environment. Except for quaternary ammonium salts, all the disinfectants at dilutions higher or equalling those recommended by the manufacturer were adequate to suppress P. aeruginosa. Chlorhexidine-, povidone-iodine- and glutaraldehyde-based disinfectants at dilutions 4 to 8-fold lower than the normal use dilution had a marked bactericidal effect ( > 3 log10 reduction of viable cells) within a short time (10 to 120 min). Similar formulations produced by different manufacturers exhibited comparable activity against P. aeruginosa.

Entities: Chemical Species

Mesh：

Substances：
Disinfectants

Year: 1995 PMID： 8549714 DOI： 10.1007/bf01721232

Source DB: PubMed Journal: Eur J Epidemiol ISSN： 0393-2990 Impact factor: 8.082

13 in total

1. Epidemiological typing of uropathogenic Pseudomonas aeruginosa strains from hospitalized patients.

Authors: P Visca; F Chiarini; C Vetriani; A Mansi; L Serino; N Orsi
Journal: J Hosp Infect Date: 1991-11 Impact factor: 3.926

2. In vitro susceptibility of hospital isolates of various bacterial genera to chlorhexidine.

Authors: T L Pitt; M A Gaston; P N Hoffman
Journal: J Hosp Infect Date: 1983-06 Impact factor: 3.926

3. Sensitivities of wild-type and envelope-defective strains of Escherichia coli and Pseudomonas aeruginosa to antibacterial agents.

Authors: B M El-Falaha; A D Russell; J R Furr
Journal: Microbios Date: 1983

2. High-level tolerance to triclosan may play a role in Pseudomonas aeruginosa antibiotic resistance in immunocompromised hosts: evidence from outbreak investigation.

Authors: Silvia D'Arezzo; Simone Lanini; Vincenzo Puro; Giuseppe Ippolito; Paolo Visca
Journal: BMC Res Notes Date: 2012-01-19

2 in total

In vitro activity of commercially manufactured disinfectants against Pseudomonas aeruginosa.

1. Epidemiological typing of uropathogenic Pseudomonas aeruginosa strains from hospitalized patients.

2. In vitro susceptibility of hospital isolates of various bacterial genera to chlorhexidine.

3. Sensitivities of wild-type and envelope-defective strains of Escherichia coli and Pseudomonas aeruginosa to antibacterial agents.

4. Isolation of chlorhexidine-resistant Pseudomonas aeruginosa from clinical lesions.

5. Investigations into the survival of Pseudomonas aeruginosa in poloxamer-iodine.

6. Nosocomial Pseudomonas cepacia infection associated with chlorhexidine contamination.

7. Resistance of Pseudomonas to quaternary ammonium compounds. I. Growth in benzalkonium chloride solution.

Review 8. Epidemiology of infections due to Pseudomonas aeruginosa.

9. Activity of antiseptics against biofilms of mixed bacterial species growing on silicone surfaces.

10. Lack of association between clinical and environmental isolates of Pseudomonas aeruginosa in hospital wards.

1. Effect of disinfectants on the metabolism of Salmonella enterica serovar enteritidis.

2. High-level tolerance to triclosan may play a role in Pseudomonas aeruginosa antibiotic resistance in immunocompromised hosts: evidence from outbreak investigation.