Literature DB >> 8548383

Pulmonary antiallergic and antiinflammatory effects of a novel, orally-active phosphodiesterase IV inhibitor (WAY-127093B) in guinea pigs and rats.

R E Howell1, S L Woeppel, D E Howell, E B Rubin, L P Jenkins, J M Golankiewicz, L J Lombardo, R J Heaslip.   

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Year:  1995        PMID： 8548383     DOI： 10.1007/bf01778317

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


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  8 in total

1.  Effect of acute and chronic antigen inhalation on airway morphology and responsiveness in actively sensitized rats.

Authors:  J C Kips; C A Cuvelier; R A Pauwels
Journal:  Am Rev Respir Dis       Date:  1992-06

2.  Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs.

Authors:  R E Howell; B D Sickels; S L Woeppel; L P Jenkins; E B Rubin; B M Weichman
Journal:  J Pharmacol Exp Ther       Date:  1994-01       Impact factor: 4.030

3.  Inflammatory cell populations in the airways and parenchyma after antigen challenge in the rat.

Authors:  P M Renzi; R Olivenstein; J G Martin
Journal:  Am Rev Respir Dis       Date:  1993-04

4.  Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.

Authors:  D C Underwood; R R Osborn; L B Novak; J K Matthews; S J Newsholme; B J Undem; J M Hand; T J Torphy
Journal:  J Pharmacol Exp Ther       Date:  1993-07       Impact factor: 4.030

5.  Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs.

Authors:  R E Howell; B D Sickels; S L Woeppel
Journal:  J Pharmacol Exp Ther       Date:  1993-02       Impact factor: 4.030

6.  Model of bronchial allergic inflammation in the brown Norway rat. Pharmacological modulation.

Authors:  J P Tarayre; M Aliaga; M Barbara; N Tisseyre; S Vieu; J Tisne-Versailles
Journal:  Int J Immunopharmacol       Date:  1992-07

7.  Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641.

Authors:  R J Heaslip; L J Lombardo; J M Golankiewicz; B A Ilsemann; D Y Evans; B D Sickels; J K Mudrick; J Bagli; B M Weichman
Journal:  J Pharmacol Exp Ther       Date:  1994-02       Impact factor: 4.030

8.  Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized brown-Norway rats.

Authors:  W Elwood; J O Lötvall; P J Barnes; K F Chung
Journal:  J Allergy Clin Immunol       Date:  1991-12       Impact factor: 10.793
  8 in total
  1 in total

Review 1.  Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?

Authors:  M A Giembycz
Journal:  Drugs       Date:  2000-02       Impact factor: 9.546
  1 in total

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