Literature DB >> 8548370

A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX2).

R Huff1, P Collins, S Kramer, K Seibert, C Koboldt, S Gregory, P Isakson.   

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Year:  1995        PMID： 8548370     DOI： 10.1007/bf01778304

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


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  4 in total

1.  A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia.

Authors:  K Hargreaves; R Dubner; F Brown; C Flores; J Joris
Journal:  Pain       Date:  1988-01       Impact factor: 6.961

Review 2.  Renal syndromes associated with nonsteroidal antiinflammatory drugs.

Authors:  D M Clive; J S Stoff
Journal:  N Engl J Med       Date:  1984-03-01       Impact factor: 91.245

Review 3.  Review article: non-steroidal, anti-inflammatory drugs--the extending scope of gastrointestinal side effects.

Authors:  L Aabakken
Journal:  Aliment Pharmacol Ther       Date:  1992-04       Impact factor: 8.171

4.  NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro.

Authors:  N Futaki; S Takahashi; M Yokoyama; I Arai; S Higuchi; S Otomo
Journal:  Prostaglandins       Date:  1994-01
  4 in total
  3 in total

1.  Cyclooxygenase enzyme activity does not impair respiratory motor plasticity after one night of intermittent hypoxia.

Authors:  Adrianne G Huxtable; Elizabeth Kopp; Brendan J Dougherty; Jyoti J Watters; Gordon S Mitchell
Journal:  Respir Physiol Neurobiol       Date:  2017-12-09       Impact factor: 1.931

2.  Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane.

Authors:  N Yoshimi; M Shimizu; K Matsunaga; Y Yamada; K Fujii; A Hara; H Mori
Journal:  Jpn J Cancer Res       Date:  1999-04

3.  The COX-2-Selective Antagonist (NS-398) Inhibits Choroidal Neovascularization and Subretinal Fibrosis.

Authors:  Ruoshuang Zhang; Zheli Liu; Han Zhang; Yi Zhang; Dong Lin
Journal:  PLoS One       Date:  2016-01-13       Impact factor: 3.240
  3 in total

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