Literature DB >> 8547307

Cloning and sequencing of a tpr-met oncogene cDNA isolated from MNNG-transformed human XP fibroblasts.

R Wicker1, A Bounacer, A Gascon, O Brison, A Sarasin, H G Suárez.   

Abstract

A rearranged tpr-met oncogene was identified in a MNNG-transformed human Xeroderma pigmentosum (XP) cell line (ASKMN). A 2016 bp cDNA was cloned and sequenced, disclosing an ORF with a coding capacity for a 523 aa protein. The sequence of this tpr-met cDNA was very similar to that previously reported in another human MNNG-transformed cell line (MNNG-HOS).

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Year:  1995        PMID: 8547307     DOI: 10.1016/0167-4781(95)00174-3

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  1 in total

1.  MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma.

Authors:  Xinyuan Lu; Nir Peled; John Greer; Wei Wu; Peter Choi; Alice H Berger; Sergio Wong; Kuang-Yu Jen; Youngho Seo; Byron Hann; Angela Brooks; Matthew Meyerson; Eric A Collisson
Journal:  Cancer Res       Date:  2017-05-18       Impact factor: 12.701

  1 in total

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