Literature DB >> 8545234

Synthesis of two peptide scorpion toxins and their use to investigate the aortic tissue regulation.

G K Tóth1, J Pataricza, T Janáky, M Mák, M Zarándi, J G Papp, B Penke.   

Abstract

The 37 amino acid residue polypeptides iberiotoxin and charybdotoxin, which contain three disulfide bridges, were chemically synthesized and characterized. The physiological effectiveness of these peptides was tested on rabbit aorta in vitro.

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Year:  1995        PMID： 8545234     DOI： 10.1016/0196-9781(95)02007-j

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  3 in total

1.  Scorpion toxins for the reversal of BoNT-induced paralysis.

Authors:  Colin A Lowery; Michael Adler; Andrew Borrell; Kim D Janda
Journal:  Bioorg Med Chem Lett       Date:  2013-10-25       Impact factor: 2.823

2.  Synthesis of a biotin derivative of iberiotoxin: binding interactions with streptavidin and the BK Ca2+-activated K+ channel expressed in a human cell line.

Authors:  Jon-Paul Bingham; Shumin Bian; Zhi-Yong Tan; Zoltan Takacs; Edward Moczydlowski
Journal:  Bioconjug Chem       Date:  2006 May-Jun       Impact factor: 4.774

3.  Synthesis of an iberiotoxin derivative by chemical ligation: a method for improved yields of cysteine-rich scorpion toxin peptides.

Authors:  Jon-Paul Bingham; Joycelyn B Chun; Margaret R Ruzicka; Qing X Li; Zhi-Yong Tan; Yuri A Kaulin; Darren R Englebretsen; Edward G Moczydlowski
Journal:  Peptides       Date:  2009-03-26       Impact factor: 3.750
  3 in total

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