Literature DB >> 8543609

Acetabular changes in an experimental model of developmental dysplasia of the hip (DDH).

B J Greenhill1, B Hainau, R D Ellis, R M el-Sayed.   

Abstract

We wished to correlate the morphological acetabular changes in developmental dysplasia of the hip (DDH) with changes at the tissue level. A secondary aim was to develop a way of measuring the dysplastic acetabulum. We studied the changes in rabbit acetabula after maintaining knee extension, measuring the major diameter from the acetabular notch to the farthest opposite point on the acetabular margin. The minor diameter was at right angles to this. The dysplastic acetabula showed elongation along the major diameter compared to control hips. Microscopic sections were made along major and minor diameters. The posterosuperior lip of the dysplastic acetabulum showed an early eversion of the acetabular cartilage. Growth of the articular cartilage in this new direction accounted for the acetabular elongation. As well as providing insight into the manner of acetabular shape change, the findings suggest the nature of remodeling required before normal acetabular growth can resume during treatment.

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Year:  1995        PMID: 8543609     DOI: 10.1097/01241398-199511000-00012

Source DB:  PubMed          Journal:  J Pediatr Orthop        ISSN: 0271-6798            Impact factor:   2.324


  8 in total

1.  Femoral trochlear groove development after patellar subluxation and early reduction in growing rabbits.

Authors:  Shengjie Wang; Gang Ji; Xu Yang; Xiaomeng Wang; Ruipeng Wang; Mei Li; Fei Wang; Chengliang Dai; Xiaona Li
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-10-11       Impact factor: 4.342

2.  A comparison of biomechanical changes on femoral head following rotational acetabular osteotomy and eccentric rotational acetabular osteotomy in normal cadaveric hip.

Authors:  Ziqing Li; Shiming Yu; Changhe Hou; Yi Chen; Yangchun Zhang; Qiyi Zhai; Bo Bai; Puyi Sheng
Journal:  Eur J Orthop Surg Traumatol       Date:  2013-01-10

3.  Reduced dynamic loads due to hip dislocation induce acetabular cartilage degeneration by IL-6 and MMP3 via the STAT3/periostin/NF-κB axis.

Authors:  Yutaka Nakamura; Mitsuru Saitou; Shingo Komura; Kazu Matsumoto; Hiroyasu Ogawa; Takaki Miyagawa; Takashi Saitou; Takeshi Imamura; Yuuki Imai; Hiroshi Takayanagi; Haruhiko Akiyama
Journal:  Sci Rep       Date:  2022-07-16       Impact factor: 4.996

4.  Early articular cartilage degeneration in a developmental dislocation of the hip model results from activation of β-catenin.

Authors:  Bo Ning; Jun Sun; Yi Yuan; Jie Yao; Peng Wang; Ruixue Ma
Journal:  Int J Clin Exp Pathol       Date:  2014-03-15

5.  Early acetabular cartilage degeneration in a rabbit model of developmental dysplasia of the hip.

Authors:  Xiangxin Zhang; Qingxia Meng; Ruixue Ma; Guangxiang Chen; Liang Cheng; Jun Shen
Journal:  Int J Clin Exp Med       Date:  2015-08-15

6.  Patella morphological alteration after patella instability in growing rabbits.

Authors:  Jinghui Niu; Qi Qi; Yingzhen Niu; Conglei Dong; Zhenyue Dong; Peng Cui; Fei Wang
Journal:  J Orthop Surg Res       Date:  2017-07-11       Impact factor: 2.359

7.  THE ROUND LIGAMENT IN DEVELOPMENTAL HIP DYSPLASIA: ARE ITS MECHANICAL AND HISTOLOGICAL PROPERTIES PRESERVED?

Authors:  Alexandre Zuccon; Hamilton DA Rosa Pereira; Sérgio Alexandre Alcântara Dos Santos; Sérgio Luís Felisbino; Luís Antônio Justulin Junior; Daniele Cristina Cataneo
Journal:  Acta Ortop Bras       Date:  2022-01-28       Impact factor: 0.513

8.  Cellular and molecular changes to chondrocytes in an in vitro model of developmental dysplasia of the hip‑an experimental model of DDH with swaddling position.

Authors:  Bo Ning; Rui Jin; Lin Wan; Dahui Wang
Journal:  Mol Med Rep       Date:  2018-08-13       Impact factor: 2.952

  8 in total

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